Galactocele in Male Infants: Report of Two Cases and Review of the Literature

Introduction

Galactocele is defined as a cystic enlargement of the mammary gland containing milk or milk-like fluid.[1] [2] It is an uncommon benign breast lesion that generally occurs in young women during or after lactation.[1] [2] [3] [4] [5] Galactocele is a very rare cause of breast enlargement in infants and children, resulting in difficulties in making the accurate diagnosis.[2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [21] [22] We report two cases of unilateral galactocele in young healthy boys, and review the literature concerning this rare condition.

• References

• 1 Winkler JM. Galactocele of the breast. Am J Surg 1964; 108: 357-360
• 2 Perez-Boscollo AC, Dutra RA, Sabino Borges LG , et al. Galactocele: An unusual case of breast enlargement in children. J Pediatr Surg 2009; 44: E1-E3
• 3 Doneray H, Ozkan B, Erdogan F , et al. Bilateral galactocele in a male infant. Turk J Med Sci 2008; 38: 481-483
• 4 Boyle M, Lakhoo K, Ramani P. Galactocele in a male infant: case report and review of literature. Pediatr Pathol 1993; 13 (3) 305-308
• 5 Obrist P, Schwabegger A, Brunhuber T, Schäfer G, Kreczy A. Galactocele in a young male patient. Plast Reconstr Surg 2003; 112 (1) 186-188
• 6 Carpenter G. Milk cyst in the breast of a male child, aged eighteen months. Rep Soc Study Dis Child 1906; 6: 162
• 7 Bessman SP, Lucas JC. Galactocele in male infant. Pediatrics 1953; 11 (2) 109-112
• 8 Steiner MM. Bilateral galactocele in a male infant. J Pediatr 1967; 71 (2) 240-243
• 9 Vanderschueren-Lodeweyckx M, Gielen ML, Eggermont E , et al. Unilateral galactocoele in a male infant. Helv Paediatr Acta 1979; 34 (6) 617-624
• 10 Cattani G. On the study of galactocele. Ann Ostet Ginec Pediatr 1880; 2: 420-431
• 11 Cousin J, Ryckewaert Ph, Picot X , et al. Galactocèle chez un nourisson masculin de neuf mois. J Sci Med Lille 1981; 99: 321-324
• 12 Cuvelier B, Zouari A, Nocton F. [Bilateral galactocele in an infant]. Arch Fr Pediatr 1984; 41 (3) 191-192
• 13 Pettinato G, Manivel JC, Kelly DR , et al. Lesions of the breast in children exclusive of typical fibroadenoma and gynecomastia. A clinicopathologic study of 13 cases. Pathol Annu 1989; 24: 296-328
• 14 Visvanathan R. Galactocoele of childhood—a case report. Singapore Med J 1990; 31 (5) 500-501
• 15 Saray A, Aydin O, Ozer C, Tamer L. Galactocele: a rare cause of breast enlargement in an infant. Plast Reconstr Surg 2001; 108 (4) 972-975
• 16 Cesur Y, Caksen H, Demirtaş I, Kösem M, Uner A, Ozer R. Bilateral galactocele in a male infant: a rare cause of gynecomastia in childhood. J Pediatr Endocrinol Metab 2001; 14 (1) 107-109
• 17 Ersoy B, Yoleri L, Riza Kandiloğglu A. Unilateral galactocele in a male infant. Plast Reconstr Surg 2002; 109 (1) 401-402
• 18 Al Salem AH, Al Nazer M. An unusual cause of breast enlargement in a 5-year-old boy. Pediatr Pathol Mol Med 2002; 21 (5) 485-489
• 19 Rahman N, Davenport M, Buchanan C. Galactocele in a male infant with congenital hypopituitarism. J Pediatr Endocrinol Metab 2004; 17 (10) 1451-1453
• 20 Welch ST, Babcock DS, Ballard ET. Sonography of pediatric male breast masses: gynecomastia and beyond. Pediatr Radiol 2004; 34 (12) 952-957
• 21 Tomasi PA, Fanciulli G, Casti T, Delitala G. Persistent hyperprolactinemia and bilateral galactocele in a male infant. Int J Pediatr Endocrinol 2009; 2009: 578610
• 22 de Chadarévian J-P, Arthur LG, Rezvani GA, Duke DS, Davis WJ, Faerber EN. The galactocele of male infants: an intriguing entity. Study and reflection about a case, with review of the literature. Pediatr Dev Pathol 2011; 14 (2) 144-148
• 23 Gómez A, Mata JM, Donoso L, Rams A. Galactocele: three distinctive radiographic appearances. Radiology 1986; 158 (1) 43-44
• 24 Weinstein SP, Conant EF, Orel SG, Zuckerman JA, Bellah R. Spectrum of US findings in pediatric and adolescent patients with palpable breast masses. Radiographics 2000; 20 (6) 1613-1621