Rationale Antibiotikatherapie in der ambulanten medizinischen Versorgung

• Literatur

• 1 (EMA) ECfDPaICEatEMA. ECDC/EMA Joint Technical Report 2009: The bacterial challenge- time to react. Im Internet: http://www.ecdc.europa.eu/en/publications/Publications/0909_TER_The_Bacterial_Challenge_Time_to_React.pdf Stand: August 2012
• 2 (BVL) BfVuL. GERMAP 2010 – Antibiotika-Resistenz und -Verbrauch. Bericht über den Antibiotikaverbrauch und die Verbreitung von Antibiotikaresistenzen in der Human- und Veterinärmedizin in Deutschland. Im Internet: http://www.p-e-g.org/econtext/germap Stand: August 2012
• 3 (BVL) BfVuL. GERMAP 2008 – Antibiotika-Resistenz und -Verbrauch. Bericht über den Antibiotikaverbrauch und die Verbreitung von Antibiotikaresistenzen in der Human- und Veterinärmedizin in Deutschland. Im Internet: http://www.bvl.bund.de/SharedDocs/Downloads/08_PresseInfothek/Germap_2008.html?nn=1461380 Stand: August 2012
• 4 De With KSH, Meyer E, Nink K et al. Antibiotikaanwendung in Deutschland im europäischen Vergleich. Dtsch Med Wochenschr 2004; 129: 1987-1992
• 5 Adriaenssens N, Coenen S, Versporten A et al. European Surveillance of Antimicrobial Consumption (ESAC): outpatient antibiotic use in Europe (1997–2009). J Antimicrob Chemother 2011; 66 (Suppl. 06) vi3-12
• 6 ECDC. Annual Epidemiological Report 2011. Reporting on 2009 surveillance data and 2010 epidemic intelligence data. Im Internet: http://www.ecdc.europa.eu/en/publications/Publications/Forms/ECDC_DispForm.aspx?ID=767 Stand: August 2012
• 7 Goossens H, Ferech M, Vander Stichele R et al. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 2005; 365: 579-587
• 8 Schröder H, Nink K, Günther J et al. Antibiotika: Solange sie noch wirken. GGW 2003; 3: 7-16
• 9 Günther J, Kern WV, Nink K et al. Solange sie noch wirken...Analyse und Kommentare zum Antbiotikaverbrauch in Deutschland. Bonn und Freiburg: Wissenschaftliches Institut der AOK (WIdo)/Universität Freiburg; 2010
• 10 Adriaenssens N, Coenen S, Versporten A et al. European Surveillance of Antimicrobial Consumption (ESAC): quality appraisal of antibiotic use in Europe. J Antimicrob Chemother 2011; 66 (Suppl. 06) vi71-77
• 11 Goossens H, Grabein B. Prevalence and antimicrobial susceptibility data for extended-spectrum beta-lactamase- and AmpC-producing Enterobacteriaceae from the MYSTIC Program in Europe and the United States (1997–2004). Diagn Microbiol Infect Dis 2005; 53: 257-264
• 12 Aldeyab MA, Harbarth S, Vernaz N et al. The impact of antibiotic use on the incidence and resistance pattern of ESBL-producing bacteria in primary and secondary healthcare settings. Br J Clin Pharmacol 2011;
• 13 File Jr TM, Hadley JA. Rational use of antibiotics to treat respiratory tract infections. Am J Managed Care 2002; 8: 713-727
• 14 Cooper RJ, Hoffman JR, Bartlett JG et al. Principles of appropriate antibiotic use for acute pharyngitis in adults: background. Ann Emergency Med 2001; 37: 711-719
• 15 S3-Leitlinie der Paul-Ehrlich-Gesellschaft für Chemotherapie dDGfPuB, der Deutschen Gesellschaft für Infektiologie und vom Kompetenznetzwerk CAPNETZ. Epidemiologie, Diagnostik, antimikrobielle Therapie und Management von erwachsenen Patienten mit ambulant erworbenen unteren Atemwegsinfektionen sowie ambulant erworbener Pneumonie – Update 2009. Pneumologie 2009; 63: e1-e68
• 16 Johnston SL, Blasi F, Black PN et al. The effect of telithromycin in acute exacerbations of asthma. N Eng J Med 2006; 354: 1589-1600
• 17 van Driel ML, De Sutter AI, Keber N et al. Different antibiotic treatments for group A streptococcal pharyngitis. Cochrane Database Syst Rev 2010;
• 18 von Baum H, Welte T, Marre R et al. Mycoplasma pneumoniae pneumonia revisited within the German Competence Network for Community-acquired pneumonia (CAPNETZ). BMC Infect Dis 2009; 9: 62
• 19 Wellinghausen N, Straube E, Freidank H et al. Low prevalence of Chlamydia pneumoniae in adults with community-acquired pneumonia. Int J Med Microbiol 2006; 296: 485-491
• 20 Welte TMR, Suttorp N. What is new in the treatment of community acquired pneumonia?. Med Klin (Munich) 2006; 101: 313-320
• 21 Wagenlehner FM, Schmiemann G, Hoyme U et al. [National S3 guideline on uncomplicated urinary tract infection: recommendations for treatment and management of uncomplicated community-acquired bacterial urinary tract infections in adult patients]. Der Urologe, Ausg A 2011; 50: 153-169
• 22 Christ-Crain M, Jaccard-Stolz D, Bingisser R et al. Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial. Lancet 2004; 363: 600-607
• 23 Muller B, Becker KL, Schachinger H et al. Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit. Crit Care Med 2000; 28: 977-983
• 24 Müller B, Schuetz P, Christ-Crain M. Procalcitonin. Schweizer Medizin-Forum 2008; 8: 388-390
• 25 Stolz D, Christ-Crain M, Bingisser R et al. Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy. Chest 2007; 131: 9-19
• 26 Briel M, Schuetz P, Mueller B et al. Procalcitonin-guided antibiotic use vs a standard approach for acute respiratory tract infections in primary care. Arch Internal Med 2008; 168: 2000-2007 discussion 2007-2008
• 27 Burkhardt O, Ewig S, Haagen U et al. Procalcitonin guidance and reduction of antibiotic use in acute respiratory tract infection. Eur Respir J 2010; 36: 601-607
• 28 Schuetz P, Chiappa V, Briel M et al. Procalcitonin algorithms for antibiotic therapy decisions: a systematic review of randomized controlled trials and recommendations for clinical algorithms. Arch Internal Med 2011; 171: 1322-1331
• 29 Diederichsen HZ, Skamling M, Diederichsen A et al. Randomised controlled trial of CRP rapid test as a guide to treatment of respiratory infections in general practice. Scand J Primary Health Care 2000; 18: 39-43
• 30 Dahler-Eriksen BS, Lauritzen T, Lassen JF et al. Near-patient test for C-reactive protein in general practice: assessment of clinical, organizational, and economic outcomes. Clin Chem 1999; 45: 478-485
• 31 Bjerrum L, Gahrn-Hansen B, Munck AP. C-reactive protein measurement in general practice may lead to lower antibiotic prescribing for sinusitis. Br J Gen Pract 2004; 54: 659-662
• 32 Hansen JG, Schmidt H, Grinsted P. Randomised, double blind, placebo controlled trial of penicillin V in the treatment of acute maxillary sinusitis in adults in general practice. Scand J Prim Health Care 2000; 18: 44-47
• 33 Bjerrum L, Cots JM, Llor C et al. Effect of intervention promoting a reduction in antibiotic prescribing by improvement of diagnostic procedures: a prospective, before and after study in general practice. Eur J Clin Pharmacol 2006; 62: 913-918
• 34 Arnold SR, Straus S. Interventions to improve antibiotic prescribing practices in ambulatory care. Cochrane Database of Systematic Reviews 2009; 1-79
• 35 Cabana MD, Rand CS, Powe NR et al. Why don’t physicians follow clinical practice guidelines? A framework for improvement.. J Amer Med Assoc 1999; 282: 1458-1465
• 36 André M, Vernby Å, Berg J et al. A survey of public knowledge and awareness related to antibiotic use and resistance in Sweden. Journal Antimicrob Chemother 2010; 65: 1292-1296
• 37 Bjerrum L, Munck A, Gahrn-Hansen B et al. Health alliance for prudent antibiotic prescribing in patients with respiratory tract infections (HAPPY AUDIT) – impact of a non-randomised multifaceted intervention programme. BMC Family Pract 2011; 12: 52
• 38 Butler CC, Simpson SA, Dunstan F et al. Effectiveness of multifaceted educational programme to reduce antibiotic dispensing in primary care: practice based randomised controlled trial. Br Med J 2012; 344: d8173
• 39 Altiner A, Brockmann S, Sielk M et al. Reducing antibiotic prescriptions for acute cough by motivating GPs to change their attitudes to communication and empowering patients: a cluster-randomized intervention study. Journal Antimicrob Chemother 2007; 60: 638-644
• 40 Faber MS, Heckenbach K, Velasco E et al. Antibiotics for the common cold: expectations of Germany’s general population. Euro surveillance : bulletin europeen sur les maladies transmissibles = European communicable disease bulletin. 2010: 15
• 41 Velasco E, Espelage W, Faber M et al. A national cross-sectional study on socio-behavioural factors that influence physicians’ decisions to begin antimicrobial therapy. Infection 2011; 39: 289-297
• 42 Velasco E, Ziegelmann A, Eckmanns T et al. Eliciting views on antibiotic prescribing and resistance among hospital and outpatient care physicians in Berlin, Germany: results of a qualitative study. Br Med J open 2012; 2 e000398
• 43 Weber JT, Courvalin P. An emptying quiver: antimicrobial drugs and resistance. Emerg Infect Dis 2005; 11: 791-793
• 44 Levy-Hara G, Amábile-Cuevas CF, Gould I et al. on behalf of the International Society of Chemotherapy Antimicrobial Stewardship Working Group. „Ten Commandments“ for the appropriate use of antibiotics by the practicing physician in an outpatient setting. Front Microbiol 2011; 2: 1-7