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Synthesis 2012; 44(17): 2743-2753
DOI: 10.1055/s-0032-1316579
DOI: 10.1055/s-0032-1316579
paper
Synthetic Studies toward Ecteinascidin 743 (Trabectedin)
Further Information
Publication History
Received: 01 May 2012
Accepted after revision: 31 May 2012
Publication Date:
06 July 2012 (online)
Abstract
An alternative synthetic route to an intermediate in the synthesis of ecteinascidin 743 has been established by using a Pictet–Spengler reaction and a Friedel–Crafts type reaction.
Key words
alkaloids - anticancer drugs - Pictet–Spengler reaction - Friedel–Crafts reaction - total synthesisSupporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information
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