Synthesis of the Structure Proposed for Natural Meliloester

Abstract

In an attempt to establish the absolute configuration of meliloester, a natural product isolated from Melilotus alba, the literature structure was synthesized in an enantiopure form. Unexpectedly, the ¹H and ¹³C NMR data was completely incompatible with those reported for the natural product. The corresponding m-hydroxy isomer was also excluded as the structure for the natural product.

Key words

esters - alcohols - natural products - aldol - phenols

• References

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