Synthesis 2012; 44(20): 3161-3164
DOI: 10.1055/s-0032-1316992
paper
© Georg Thieme Verlag Stuttgart · New York

Heck Reaction of Baylis–Hillman Adducts with Iodobenzenes Using a Catalytic Amount of Pd/C under Solvent-Free Conditions

Hyun-Soo Kim
Department of Advanced Material Chemistry, Korea University, Jochiwon, Choongnam 339-770, South Korea, Fax: +82(42)8675396   Email: cmyoon@korea.ac.kr
,
Sang-Jin Lee
Department of Advanced Material Chemistry, Korea University, Jochiwon, Choongnam 339-770, South Korea, Fax: +82(42)8675396   Email: cmyoon@korea.ac.kr
,
Boram Choi
Department of Advanced Material Chemistry, Korea University, Jochiwon, Choongnam 339-770, South Korea, Fax: +82(42)8675396   Email: cmyoon@korea.ac.kr
,
Cheol Min Yoon*
Department of Advanced Material Chemistry, Korea University, Jochiwon, Choongnam 339-770, South Korea, Fax: +82(42)8675396   Email: cmyoon@korea.ac.kr
› Author Affiliations
Further Information

Publication History

Received: 23 May 2012

Accepted after revision: 10 July 2012

Publication Date:
12 September 2012 (online)


Abstract

The reaction of Baylis–Hillman adducts with iodobenzenes using commercially available palladium-on-carbon as a catalyst under solvent-free conditions afforded the corresponding coupling products, α-benzyl-β-keto esters, in high to excellent yields. The reactions are very efficient.

 
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