One-Pot Access to Cinnamates via Direct Oxidative C–H Transformation of Allylarenes

Meng-Yang Chang; Shin-Ying Lin; Chieh-Kai Chan

doi:10.1055/s-0032-1318146

Synlett, Inhaltsverzeichnis

Synlett 2013; 24(4): 487-490
DOI: 10.1055/s-0032-1318146

letter

One-Pot Access to Cinnamates via Direct Oxidative C–H Transformation of Allylarenes

Meng-Yang Chang*

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan Fax: +886(7)3125339 eMail: mychang@kmu.edu.tw

,

Shin-Ying Lin

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan Fax: +886(7)3125339 eMail: mychang@kmu.edu.tw

,

Chieh-Kai Chan

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan Fax: +886(7)3125339 eMail: mychang@kmu.edu.tw

› Institutsangaben

Abstract

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Abstract

A highly selective combination of ruthenium complex and oxidant, which catalyzes the oxidative C–H esterification of allylarenes to the corresponding bis-(E)-cinnamates and (E)-cinnamates, is described. The one-pot route was carried out by olefinic migration of allylarenes with RuCl₂(PPh₃)₃ and DDQ-mediated allylic oxidation of the resulting internal alkenes with various alcohols in good yields.

Key words

allylarenes - C–H esterification - cinnamates

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Referenzen

References and Notes

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