Enantiomerically Pure Allylboronic Esters as Versatile Reagents in the Enantioselective Synthesis of Dihydro-α-pyrone-Containing Natural Products

Abstract

A short and efficient enantio- and diastereoselective synthesis­ of different representatives from the class of dihydro-α-pyrone natural products, including both enantiomers of goniothalamin, massoia lactone, parasorbic acid, and some derivatives is presented. It is based on the application of enantiopure α-chiral allylboronic esters in allyl additions.

Key words

natural products - goniothalamin - allyl addition - boronic ester - dihydro-α-pyrones

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