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J Neurol Surg A Cent Eur Neurosurg 2013; 74(S 01): e13-e17
DOI: 10.1055/s-0032-1320024
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Solitary Plasmacytoma Presenting as an Intramedullary Mass of the Cervical Cord

Franz Josef Hans
1   Department of Neurosurgery, University Hospital (RWTH), Aachen, Germany
,
Sasikhan Geibprassert
2   Department of Neuroradiology, University of Toronto, Toronto, Ontario, Canada
,
Timo Krings
2   Department of Neuroradiology, University of Toronto, Toronto, Ontario, Canada
,
Joachim Weis
3   Institute of Neuropathology, RWTH Aachen University, Aachen, Germany
,
Martina Deckert
4   Department of Neuropathology, University Hospital Cologne, Cologne, Germany
,
Alexander Ludolph
5   Department of Neuroradiology, University Hospital (RWTH), Aachen, Germany
,
Rainhardt Osieka
6   Department of Internal Medicine IV, University Hospital (RWTH), Aachen, Germany
,
Edgar Jost
6   Department of Internal Medicine IV, University Hospital (RWTH), Aachen, Germany
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Publikationsverlauf

15. September 2011

26. Januar 2012

Publikationsdatum:
11. Dezember 2012 (online)

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Abstract

Extramedullary plasmacytomas originating in the spinal cord are extremely rare lesions. We report a 52-year-old man presenting with progressive tetraparesis. Spinal magnetic resonance imaging (MRI) showed an ill-defined contrast-enhancing intramedullary mass at the C5-6 level. After a biopsy was taken, pathology including immunohistochemistry revealed plasmacytoma. Complete workup for multiple myeloma was negative. The patient was treated with intravenous chemotherapy followed by radiotherapy and corticosteroids without any improvement of the clinical symptoms or decreased tumor size on the follow-up MRIs. The most common spinal manifestation of plasmocytoma is involvement of the vertebral bodies leading to extradural compression of the cord. Only rarely plasmocytoma manifests itself as a primarily dural lesion leading to an intradural cord compression. This report describes the extremely rare manifestation of plasmocytoma of the spinal cord itself that therefore should be considered in the differential diagnosis of spinal cord mass lesions.

Keywords

spinal cord - intramedullary tumor - extramedullary plasmacytoma
 

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