Evaluation of natural products as potential agrochemical agents with insecticide, fungicide and herbicide activities

V Dumontet; M Litaudon; F Olivon; C Poullain; P Rasoanaivo; D Stien; V Eparvier; E Houël; N Fokialakis; M Halabalaki; AL Skaltsounis; A Espinosa; D Olmedo; M Gupta; G Fouche; M Hamburger; O Sorgenfrei; D Breuninger; F Guéritte

doi:10.1055/s-0032-1321053

Evaluation of natural products as potential agrochemical agents with insecticide, fungicide and herbicide activities

V Dumontet ¹, M Litaudon ¹, F Olivon ¹, C Poullain ², P Rasoanaivo ³, D Stien ¹, V Eparvier ¹, E Houël ⁴, N Fokialakis ⁵, M Halabalaki ⁵, AL Skaltsounis ⁵, A Espinosa ⁶, D Olmedo ⁶, M Gupta ⁶, G Fouche ⁷, M Hamburger ⁸, O Sorgenfrei ⁹, D Breuninger ⁹, F Guéritte ¹

¹Centre de Recherche de Gif, Institut de Chimie des Substances Naturelles, CNRS, 1, Avenue de la Terrasse, 91198 Gif-sur-Yvette Cedex, France
²Laboratoire des Plantes Médicinales CNRS, Centre IRD de Nouméa BP 643, 98845 Nouméa Cedex, New Caledonia
³Institut Malgache de Recherche Appliquées, Avarabohitra-Itaosy, 101 Antananarivo, Madagascar
⁴CNRS – UMR EcoFoG, Campus Agronomique, F-97379 Kourou, France
⁵Department of Pharmacognosy & Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Panepistimiopolis Zografou, Athens, 15771, Greece
⁶Center for Pharmacognostic Research on Panamanian Flora, College of Pharmacy, Apartado 0824–00172, Panama
⁷CSIR, Biosciences, Building 20, Meiring Naude Road, Brummeria, Pretoria, 0001, South Africa
⁸Division of Pharmaceutical Biology, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland
⁹BASF SE, APR/HP – Li721, D-67117 Limburgerhof, Germany

Abstract

The present work aims to identify new promising plant sources, which could be exploited for their agrochemical properties. A total of 484 natural products from academic libraries were selected for screening against four fungal pathogens, five insects and two plants. On the basis of the hits founded and a literature survey, the flora of source countries (New Caledonia, French Guiana, Madagascar, Panama, South Africa and Greece) was analysed for plants containing the desired scaffolds. Lists of 1800 plant part samples were thus established. The plant parts collected generated 3600 extracts that are being evaluated.