Krankenhaushygiene up2date, Table of Contents Krankenhaushygiene up2date 2012; 07(04): 275-289DOI: 10.1055/s-0032-1325954 Nosokomiale Infektionen © Georg Thieme Verlag KG Stuttgart · New YorkBeatmungsassoziierte Pneumonie – was gibt es Neues? Authors Karl Lewalter Sebastian Lemmen Simone Scheithauer Recommend Article Abstract Buy Article(opens in new window) All articles of this category(opens in new window) Full Text References Literatur 1 Safdar N, Crnich CJ, Maki D. The pathogenesis of ventilator-associated pneumonia: its relevance to developing effective strategies for prevention. Resp Care 2005; 50: 725-741 2 Pawar M, Mehta Y, Khurana P et al. Ventilator-associated pneumonia: incidence, risk factors, outcome and microbiology. J Cardiothorac Vasc Anesth 2003; 17: 22-28 3 Cook DJ, Walter SD, Cook RJ et al. Incidence of and risk factors for ventilator-associated pneumonia in critically ill adults. Ann Intern Med 1998; 129: 433-440 4 Klompas M. Does this patient have ventilator-associated pneumonia?. J Am Med Assoc 2007; 297: 1583-1593 5 Gastmeier P, Sohr D, Geffers C et al. Early- and late-onset pneumonia: is this still a useful classification?. Antimicrob Agents Chemother 2009; 53: 2714-2718 6 Tablan OC, Anderson LJ, Besser R et al. Guidelines for preventing health-care-associated pneumonia, 2003: recommendations of CDC and the Healtcare Infection Control Practices Advisory Committee. MMWR Recomm 2004; 53: 1-36 7 Kollef MH, Hamilton CW, Ernst FR. Economic impact of ventilator-associated pneumonia in a large matched cohort. Infect Control Hosp Epidemiol 2012; 33: 250-256 8 Moller AH, Hansen L, Jensen MS et al. A cost-effectiveness analysis of reducing ventilator-associated pneumonia at a Danish ICU with ventilator bundle. J Med Econ 2012; 15: 285-292 9 Timsit JF, Zahar JR, Chevret S. Attributable mortality of ventilator-associated pneumonia. Curr Opin Crit Care 2011; 17: 464-471 10 Berwick DM, Calkins DR, McCannon CJ et al. The 100000 Lives Campaign. Setting a goal and a deadline for improving health care quality. J Am Med Assoc 2006; 295: 324-327 11 Girard TD, Kress JP, Fuchs BD et al. Efficacy and safety of a paired sedation and ventilator-weaning protocol for mechanically ventilated patients in intensive care: a randomized controlled trial. Lancet 2008; 371: 126-134 12 Zuschneid I, Schwab F, Geffers C et al. Trends in ventilator-associated pneumonia rates within the German Nosocomial Infection Surveillance System (KISS). Infect Control Hosp Epidemiol 2007; 28: 314-318 13 Salahuddin N, Zafar A, Sukhyani L et al. Reducing ventilator-associated pneumonia rates through a staff education programme. J Hosp Inf 2004; 57: 223-227 14 Ferrer R, Artigas A, Levy MM et al. Improvement in process of care and outcome after a multicenter severe sepsis educational program in spain. J Am Med Assoc 2008; 299: 2294-2303 15 World Health Organization (WHO). WHO Guidelines for Hand Hygiene in Health Care. Geneva: WHO; 2009 16 Koff MD, Corwin HL, Beach ML et al. Reduction in ventilator associated pneumonia in a mixed intensive care unit after initiation of a novel hand hygiene program. J Crit Care 2011; 26: 489-495 17 Rewa O, Muscedere J. Ventilator-associated pneumonia: update on etiology, prevention and management. Curr Infect Dis Rep 2011; 13: 287-295 18 Brochard L. Mechanical ventilation: invasive versus noninvasive. Eur Respir J 2003; 22 : 31-37 19 Drakulovic M, Torres A, Bauer TT et al. Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: a randomized trial. Lancet 1999; 354: 1851-1858 20 Van Nieuwenhoven CA, Vandenbroucke-Grauls C, van Thiel FH et al. Feasibility and effects of the semirecumbent position to prevent ventilator-associated pneumonia: a randomized study. Crit Care Med 2006; 34: 396-402 21 Niel-Weise BS, Gastmeier P, Kola A et al. An evidence-based recommendation on bed head elevation for mechanically ventilated patients. Crit Care 2011; 15: R111 22 Craven DE, Lichtenberg DA, Goularte TA et al. Contaminated medication nebulizers in mechanical ventilator circuits. Am J Med 1984; 77: 834-838 23 Branson RD. The ventilator circuit and ventilator-associated pneumonia. Resp Care 2005; 50: 774-787 24 Prävention der nosokomialen Pneumonie. Bundesgesundheitsbl Gesundheitsforsch Gesundheitssch 2000; 43: 302-309 25 Han J, Liu Y. Effect of ventilator circuit changes on ventilator-associated pneumonia: a systematic review and meta-analysis. Resp Care 2010; 55: 467-474 26 Lorente L, Lecuona M, Martin M et al. Ventilator-associated pneumonia using a closed versus an open tracheal suction system. Crit Care Med 2005; 33: 115-119 27 Altintas ND, Aydin K, Türkoglu MA et al. Effect of enteral versus parenteral nutrition on outcome of medical patients requiring mechanical ventilation. Nutrition in Clinical Practice 2011; 26: 322-329 28 O’Grady NP, Alexander M, Burns LA et al. Guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis 2011; 52: 162-193 29 Morrow LE, Kollef MH, Casale TB. Probiotic prophylaxis of ventilator-associated pneumonia. Am J Respir Crit Care 2010; 182: 1058-1064 30 Gu WJ, Wei CY, Yin RX. Lack of efficacy of probiotics in preventing ventilator-associated pneumonia: a systematic review and meta-analysis of randomized controlled trials. Chest 2012; 31 Terragni PP, Antonelli M, Fumagalli R et al. Early vs late tracheotomy for prevention of pneumonia in mechanically ventilated adult ICU patients. J Am Med Assoc 2010; 303: 1483-1489 32 Hess DR. Patient positioning and ventilator-associated pneumonia. Resp Care 2005; 50: 892-898 33 Delaney A, Gray H, Laupland KB. Kinetic bed therapy to prevent nosocomial pneumonia in mechanically ventilated patients: a systematic review and meta-analysis. Crit Care 2006; 10: R70 34 Labeau SO, Van de Vyver K, Brusselaers N et al. Prevention of ventilator-associated pneumonia with oral antiseptics: a systematic review and meta-analysis. Lancet Infect Dis 2011; 11: 845-854 35 Chan EY, Ruest A, O’Meade M et al. Oral decontamination for prevention of pneumonia in mechanically ventilated adults: a systematic review and meta-analysis. Brit Med J 2007; 334: 889-1000 36 Lorente L, Lecunoa M, Jimenez A et al. Ventilator-associated pneumonia with or without toothbrushing: a randomized controlled trial. Eur J Clin Microbiol Infect Dis 2012; 31: 2621-2629 37 Schultz MJ, Haas LE. Antibiotics or probiotics as preventive measures against ventilator-associated pneumonia: a literature review. Crit Care 2011; 15: R18 38 de Smet AMGA, Kluytmans JAJW, Cooper BS et al. Decontamination of the digestive tract and oropharynx in ICU patients. N Engl J Med 2009; 360: 20-31 39 de Smet AMGA, Bonten MJM, Kluytmans JAJW. For whom should we use selective decontamination of the digestive tract?. Curr Opin Infect Dis 2012; 25: 211-217 40 Oosdijk EAN, de Smet AMGA, Blok HEM et al. Ecological effects of selective decontamination on resistant gram-negative bacterial colonization. Am J Respir Crit Care Med 2010; 181: 452-457 41 Muscedere J, Rewa O, Mckechnie K et al. Subglottic secretion drainage for the prevention of ventilator-associated pneumonia: a systematic review and meta-analysis. Crit Care Med 2011; 38: 1985-1991 42 Valencia M, Ferrer M, Farre R et al. Automatic control of tracheal tube cuff pressure in ventilated patients in semirecumbent position: a randomized trial. Crit Care Med 2007; 35: 1543-1549 43 Nseir S, Zerimech F, Fournier C et al. Continuous control of tracheal cuff pressure and microaspiration of gastric contents in critically ill patients. Am J Respir Crit Care Med 2011; 184: 1041-1047 44 Kollef MH, Afessa B, Anzueto A et al. Silver-coated endotracheal tubes and incidence of ventilator-associated pneumonia. J Am Med Assoc 2008; 300: 805-813 45 Lorente L, Blot S, Rello J. New issues and controversies in the prevention of ventilator-associated pneumonia. Am J Respir Crit Care Med 2010; 182: 870-876 46 Berra L, Coppadoro A, Bitter EA et al. A clinical assessment of the Mucus Shaver: a device to keep the endotracheal tube free from secretions. Crit Care Med 2012; 40: 119-124 47 Lorente L, Lecunoa M, Jimenez A et al. Influence of an endotracheal tube with polyurethane cuff and subglottic secretion drainage on pneumonia. Am J Crit Care Med 2007; 176: 1079-1083 48 Miller MA, Arndt JL, Konkle MA et al. A polyurethane cuffed endotracheal tube is associated with decreased rates of ventilator-associated pneumonia. J Crit Care 2011; 26: 280-286 49 Manzano F, Fernández-Mondéjar E, Colmenero M et al. Positive-end expiratory pressure reduces the incidence of ventilator-associated pneumonia in nonhypoxemic patients. Crit Care Med 2008; 36: 2225-2231 50 Schulze-Röbbecke R. Bündel zur Prävention nosokomialer Infektionen. Krankenh hyg up2date 2011; 6: 9-23 51 Al-Tawfiq JA, Abed MS. Decreasing ventilator-associated pneumonia in adult intensive care units using the Institute for Healthcare Improvement bundle. Am J Infect Control 2010; 38: 552-556 52 Morris AC, Hay AW, Swann DG et al. Reducing ventilator-associated pneumonia in intensive care: impact of implementing a care bundle. Crit Care Med 2011; 39: 2218-2224 53 Hawe CS, Ellis KS, Cairns CJS et al. Reduction of ventilator-associated pneumonia: active versus passive guideline implementation. Intensive Care Med 2009; 35: 1180-1186
