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Endoscopy 2013; 45(02): 153
DOI: 10.1055/s-0032-1326102
DOI: 10.1055/s-0032-1326102
Letters to the editor
Reply to Schoppman et al.
Further Information
Publication History
Publication Date:
30 January 2013 (online)
![](https://www.thieme-connect.de/media/endoscopy/201302/lookinside/thumbnails/10.1055-s-0032-1326102-1.jpg)
We were delighted to read the interesting letter from Professor Schoppman and colleagues. They raise two issues: pre-emptive endoscopic radiofrequency ablation (RFA) to prevent development of esophageal adenocarcinoma (EAC); and the link between Barrett’s esophagus, cardiorespiratory illness, and metabolic syndrome.
In our cohort [1], 24 % died during follow-up, and of those 16 % died from EAC, compared with 34 % from cardiovascular causes. Overall mortality was higher than expected but only due to EAC.
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References
- 1 Caygill CPJ, Royston C, Charlett A et al. Mortality in Barrett’s esophagus: three decades of experience at a single center. Endoscopy 2012; 44: 892-898
- 2 Spechler SJ. Barrett’s esophagus without dysplasia: wait or ablate?. Dig Dis Sci 2011; 56: 1926-1928
- 3 Sikkema M, Looman CWN, Steyerberg EW et al. Predictors for neoplastic progression in patients with Barrett’s esophagus: a prospective cohort study. Am J Gastroenterol 2011; 106: 1231-1238
- 4 Caygill CPJ, Royston C, Charlett A et al. Barrett’s, blood groups and progression to oesophageal cancer: is nitric oxide the link?. Eur J Gastroenterol Hepatol 2011; 23: 801-806
- 5 Bardhan KD, Strugala V, Dettmar PW. Reflux revisited: advancing the role of pepsin. Int J Otolaryngol 2012; 646901 Epub 2011 Nov 10