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Planta Med 2013; 79(02): 169-174
DOI: 10.1055/s-0032-1328022
Analytical Studies
Original Papers
Georg Thieme Verlag KG Stuttgart · New York

Fast Screening of Authentic Ginseng Products by Surface Desorption Atmospheric Pressure Chemical Ionization Mass Spectrometry

Hao Yue   *
1   Jilin Ginseng Academy, Changchun University of Chinese Medicine, Jilin, Changchun, China
,
Li Ma   *
2   Chongqing Key Laboratory for Disease Proteomics, State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Third Military Medical University, Chongqing, China
,
Zifeng Pi
3   Changchun center of Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academic of Science, Jilin, Changchun, China
,
Huanwen Chen
4   East China Institute of Technology, Department of Applied Chemistry, Jiangxi, Fuzhou, China
,
Yang Wang
1   Jilin Ginseng Academy, Changchun University of Chinese Medicine, Jilin, Changchun, China
,
Bin Hu
4   East China Institute of Technology, Department of Applied Chemistry, Jiangxi, Fuzhou, China
,
Shuying Liu
1   Jilin Ginseng Academy, Changchun University of Chinese Medicine, Jilin, Changchun, China
3   Changchun center of Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academic of Science, Jilin, Changchun, China
› Author Affiliations
Further Information

Publication History

received 23 April 2012
revised 07 October 2012

accepted 31 October 2012

Publication Date:
04 December 2012 (online)

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Abstract

Surface desorption atmospheric pressure chemical ionization mass spectrometry was developed as a rapid online detection technology for the chemical fingerprints of ginseng products without any sample pretreatment. More than 20 ginsenosides were detected in the ginseng tissue and identified by their tandem mass spectrometry. Data were well matched with their reference compounds. Herein, surface desorption atmospheric pressure chemical ionization mass spectrometry was first applied to study the nonvolatile compounds in ginseng. White and red ginseng have been successfully differentiated from their counterfeits using some ginsenosides as chemical markers. Ginsenoside can be used to differentiate between white ginseng, red ginseng, unboiled ginseng, and their counterfeits. Ginsenosides Ra1–3, Rb2-3, and Rc might be used to differentiate between white ginseng and boiled ginseng. Our result showed that surface desorption atmospheric pressure chemical ionization mass spectrometry not only could be used for fast screening authentic ginseng products but also might become a useful promising technique for the characterization of nonvolatile compounds in medicinal herbs to save researchers the laborious effort of sample pretreatment.

Key words

Panax species - Araliaceae - ginseng - ginsenoside - chemical marker - surface desorption atmospheric pressure chemical ionization - mass spectrometry

* These authors contributed equally to this paper.


 

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