Fast Screening of Authentic Ginseng Products by Surface Desorption Atmospheric Pressure Chemical Ionization Mass Spectrometry

Hao Yue; Li Ma; Zifeng Pi; Huanwen Chen; Yang Wang; Bin Hu; Shuying Liu

doi:10.1055/s-0032-1328022

Planta Medica, Inhaltsverzeichnis

Planta Med 2013; 79(02): 169-174
DOI: 10.1055/s-0032-1328022

Analytical Studies

Original Papers

Georg Thieme Verlag KG Stuttgart · New York

Fast Screening of Authentic Ginseng Products by Surface Desorption Atmospheric Pressure Chemical Ionization Mass Spectrometry

Hao Yue^*

¹Jilin Ginseng Academy, Changchun University of Chinese Medicine, Jilin, Changchun, China

,

Li Ma^*

²Chongqing Key Laboratory for Disease Proteomics, State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Third Military Medical University, Chongqing, China

,

Zifeng Pi

³Changchun center of Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academic of Science, Jilin, Changchun, China

,

Huanwen Chen

⁴East China Institute of Technology, Department of Applied Chemistry, Jiangxi, Fuzhou, China

,

Yang Wang

¹Jilin Ginseng Academy, Changchun University of Chinese Medicine, Jilin, Changchun, China

,

Bin Hu

⁴East China Institute of Technology, Department of Applied Chemistry, Jiangxi, Fuzhou, China

,

Shuying Liu

¹Jilin Ginseng Academy, Changchun University of Chinese Medicine, Jilin, Changchun, China

³Changchun center of Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academic of Science, Jilin, Changchun, China

› Institutsangaben

Abstract

Surface desorption atmospheric pressure chemical ionization mass spectrometry was developed as a rapid online detection technology for the chemical fingerprints of ginseng products without any sample pretreatment. More than 20 ginsenosides were detected in the ginseng tissue and identified by their tandem mass spectrometry. Data were well matched with their reference compounds. Herein, surface desorption atmospheric pressure chemical ionization mass spectrometry was first applied to study the nonvolatile compounds in ginseng. White and red ginseng have been successfully differentiated from their counterfeits using some ginsenosides as chemical markers. Ginsenoside can be used to differentiate between white ginseng, red ginseng, unboiled ginseng, and their counterfeits. Ginsenosides Ra_1–3, Rb₂-₃, and Rc might be used to differentiate between white ginseng and boiled ginseng. Our result showed that surface desorption atmospheric pressure chemical ionization mass spectrometry not only could be used for fast screening authentic ginseng products but also might become a useful promising technique for the characterization of nonvolatile compounds in medicinal herbs to save researchers the laborious effort of sample pretreatment.

Key words

Panax species - Araliaceae - ginseng - ginsenoside - chemical marker - surface desorption atmospheric pressure chemical ionization - mass spectrometry

Volltext

Referenzen

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