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Planta Med 2013; 79(07): 580-590
DOI: 10.1055/s-0032-1328463
Women's Health
Mini Reviews
Georg Thieme Verlag KG Stuttgart · New York

Phytoestrogenic Potential of Cyclopia Extracts and Polyphenols

Ann Louw
1   Departments of Biochemistry, University of Stellenbosch, Stellenbosch, Matieland, South Africa
,
Elizabeth Joubert
2   Departments of Food Science, University of Stellenbosch, Stellenbosch, Matieland, South Africa
3   Post-Harvest and Wine Technology, ARC (Agricultural Research Council of South Africa) Infruitec-Nietvoorbij, Stellenbosch, South Africa
,
Koch Visser
1   Departments of Biochemistry, University of Stellenbosch, Stellenbosch, Matieland, South Africa
› Author Affiliations
Further Information

Publication History

received 14 December 2012
revised 19 February 2013

accepted 14 March 2013

Publication Date:
22 April 2013 (online)

Also available at
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Abstract

Cyclopia Vent. species, commonly known as honeybush, are endemic to Southern Africa. The plant is traditionally used as an herbal tea but several health benefits have recently been recorded. This minireview presents an overview of polyphenols found in Cyclopia and focusses on the phytoestrogenic potential of selected polyphenols and of extracts prepared from the plant.

Key words

Fabaceae - Cyclopia - phytoestrogen - ER binding - ERE promoter reporter assay - E-screen - uterotrophic assay
 

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