Download PDF
Thorac Cardiovasc Surg 2014; 62(01): 076-079
DOI: 10.1055/s-0032-1328920
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Use of Extracellular Matrix Materials in Patients with Endocarditis

Simon Harald Sündermann
1   Department of Cardiovascular Surgery, University Hospital Zurich, Zürich, Switzerland
,
Héctor Rodriguez Cetina Biefer
1   Department of Cardiovascular Surgery, University Hospital Zurich, Zürich, Switzerland
,
Maximilian Y. Emmert
1   Department of Cardiovascular Surgery, University Hospital Zurich, Zürich, Switzerland
,
Volkmar Falk
1   Department of Cardiovascular Surgery, University Hospital Zurich, Zürich, Switzerland
› Author Affiliations
Further Information

Publication History

26 April 2012

02 August 2012

Publication Date:
09 November 2012 (online)

    Permissions and Reprints All articles of this category

Abstract

Tissue replacement is sometimes necessary during surgery for endocarditis. Commonly used materials are Dacron, expanded polytetrafluoroethlyene, or bovine pericardium. Those materials have no potential for bioresorption and cannot restore regional functionality. Extracellular matrices became available lately as patch material. Here we present two cases of patients with endocarditis. CorMatrix ECM (CorMatrix Cardiovascular, Inc., Atlanta, Georgia, United States) was used to repair intracardiac structures with good results in follow-up up to 3 months. CorMatrix ECM may be an adequate alternative to foreign material for patients with endocarditis.

Keywords

endocarditis - heart valve surgery - bioengineering
 

  • References

  • 1 Robinson KA, Li J, Mathison M , et al. Extracellular matrix scaffold for cardiac repair. Circulation 2005; 112 (9, Suppl) I135-I143
    PubMedSearch in Google Scholar
  • 2 Frantz C, Stewart KM, Weaver VM. The extracellular matrix at a glance. J Cell Sci 2010; 123 (Pt 24) 4195-4200
    CrossrefPubMedSearch in Google Scholar
  • 3 Badylak SF, Weiss DJ, Caplan A, Macchiarini P. Engineered whole organs and complex tissues. Lancet 2012; 379 (9819) 943-952
    CrossrefPubMedSearch in Google Scholar
  • 4 van den Heever JJ, Neethling WM, Smit FE, Litthauer D, Joubert G. The effect of different treatment modalities on the calcification potential and cross-linking stability of bovine pericardium. Cell Tissue Bank 2012; March 2; doi: 10.1007/s10561-012-9299-z [Epub ahead of print]
    PubMedSearch in Google Scholar
  • 5 Vaideeswar P, Mishra P, Nimbalkar M. Infective endocarditis of the Dacron patch-a report of 13 cases at autopsy. Cardiovasc Pathol 2011; 20 (5) e169-e175
    CrossrefPubMedSearch in Google Scholar
  • 6 Badylak SF, Vorp DA, Spievack AR , et al. Esophageal reconstruction with ECM and muscle tissue in a dog model. J Surg Res 2005; 128 (1) 87-97
    CrossrefPubMedSearch in Google Scholar
  • 7 Scholl FG, Boucek MM, Chan KC, Valdes-Cruz L, Perryman R. Preliminary experience with cardiac reconstruction using decellularized porcine extracellular matrix scaffold: human applications in congenital heart disease. World J Pediatr Cong Heart Surgl 2010; 1 (1) 132-136
    PubMedSearch in Google Scholar