DMW - Deutsche Medizinische Wochenschrift, Table of Contents Dtsch Med Wochenschr 2013; 138(12): 598DOI: 10.1055/s-0032-1332929 Pro & Contra | Commentary Kardiologie © Georg Thieme Verlag KG Stuttgart · New York Die genetische Testung ist der Myokardbiopsie bei Kardiomyopathien überlegen – pro Genetic testing is superior to biopsy of the myocardium in cardiomyopathy – yes A. Thanaraj 1 Abteilung Innere Medizin III, Kardiologie, Angiologie und Pulmologie, Universitätsklinik Heidelberg, Deutschland , B. Meder 1 Abteilung Innere Medizin III, Kardiologie, Angiologie und Pulmologie, Universitätsklinik Heidelberg, Deutschland 2 DZHK (German Centre for Cardiovascular Research), Standort Heidelberg › Author Affiliations Recommend Article Abstract Buy Article Schlüsselwörter SchlüsselwörterGenetische Testung - Next-Generation Sequencing - Dilatative Kardiomyopathie (DCM) - Hypertrophische Kardiomyopathie (HCM) Keywords Keywordsgenetic testing - Next-Generation Sequencing - dilated cardiomyopathy - hypertrophic cardiomyopathy Full Text References Literatur 1 Charron P et al. Genetic counselling and testing in cardiomyopathies. Eur Heart J 2010; 31: 2715-2726 2 Gersh BJ et al. 2011 ACCF/AHA Guideline for the diagnosis and treatment of hypertrophic cardiomyopathy. J Am Coll Cardiol 2011; 3 Kuhl U, Schultheiss HP. Myocarditis. Dtsch Arztebl Int 2012; 109: 361-368 4 McMurray JJ et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012. Eur Heart J 2012; 33: 1787-1847 5 Meder B et al. Targeted next-generation sequencing for the molecular genetic diagnostics of cardiomyopathies. Circ Cardiovasc Genet 2011; 4: 110-122 6 Meune C et al. Primary prevention of sudden death in patients with lamin A/C gene mutations. N Engl J Med 2006; 354: 209-210 7 van Berlo JH et al. Meta-analysis of clinical characteristics of 299 carriers of LMNA gene mutations. J Mol Med (Berl) 2005; 83: 79-83 8 van Rijsingen IA et al. Risk factors for malignant ventricular arrhythmias in lamin a/c mutation carriers a European cohort study. J Am Coll Cardiol 2012; 59: 493-500 9 Yilmaz A et al. Comparative evaluation of left and right ventricular endomyocardial biopsy. Circulation 2010; 122: 900-909
