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J Neurol Surg A Cent Eur Neurosurg 2013; 74(S 01): e159-e165
DOI: 10.1055/s-0032-1333417
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Bilateral Ptosis as Initial Presentation of Gliomatosis Cerebri: Case Report

Timothy Kovanda
1   Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, United States
,
John Braca
1   Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, United States
,
Vikram Prabhu
1   Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, United States
› Author Affiliations
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Publication History

01 May 2012

20 October 2012

Publication Date:
20 February 2013 (online)

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Abstract

Gliomatosis cerebri is a rare, diffuse glioma of neuroepithelial origin involving more than two cerebral lobes. Clinical presentation of gliomatosis cerebri is variable and depends on the degree, extent, and location of cortical involvement. Signs and symptoms related to supratentorial cortical involvement predominate and the diagnosis is reached through a combination of clinical, radiographic, and histopathological evaluations. This is a report of a young man who presented with visual problems and bilateral ptosis, which were eventually attributed to gliomatosis cerebri. Standard radiation and chemotherapy were administered but the patient eventually succumbed to the disease. The unique clinical presentation is discussed in light of this rare neoplasm of the central nervous system.

Keywords

gliomatosis cerebri - ptosis - radiation therapy - temozolomide
 

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