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Fortschr Neurol Psychiatr 2013; 81(08): 459-463
DOI: 10.1055/s-0033-1335731
Kasuistik
© Georg Thieme Verlag KG Stuttgart · New York

Poststroke-Bipolar affektive Erkrankung

Poststroke-Bipolar Affective Disorder
S. A. Bengesser
,
W. E. Wurm
,
N. Lackner
,
A. Birner
,
B. Reininghaus
,
H.-P. Kapfhammer
,
E. Reininghaus
Further Information

Publication History

Publication Date:
12 August 2013 (online)

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Zusammenfassung

Eine junge Frau im Alter von 23 Jahren erleidet wenige Wochen nach einem Stammganglieninfarkt rechts (Globus pallidus) mit Hemiplegie links erstmalig eine ausgeprägte Manie mit Selbstgefährdung. Als Risikofaktor konnte nur die Einnahme von Kontrazeptiva festgestellt werden. Im Verlauf entwickelt sich auch bei der Mutter eine depressive Erkrankung, sodass eine gewisse genetische Prädisposition für affektive Störungen möglich ist, welche jedoch nicht allein den Ausbruch der Manie erklären würde. Ein Zusammenhang mit dem rechtsseitigen Stammganglieninfarkt und dem Ausbruch der bipolar affektiven Störung ist in der Literatur beschrieben. Auch werden vaskuläre bzw. inflammatorische Risikofaktoren in Synopsis mit der Ätiopathogenese der bipolar affektiven Störung in diesem Case-Report genauer diskutiert.

Abstract

A few weeks after suffering from a basal ganglia infarction (globus pallidus) with left-sided hemiplegia, a 23-year-old woman exhibited for the first time a pronounced mania with self-endangerment. The use of oral contraceptives was the only determinable risk factor. During the further course, the mother also developed a depressive disorder. Thus a certain genetic predisposition for affective disorders may be relevant, although this would not explain the outbreak by itself. An association between the right-sided basal ganglia infarction and the occurrence of a bipolar affective disorder has been described in the literature. Vascular or, respectively, inflammatory risk factors in synopsis with the aetiopathogenesis of bipolar affective disorders are also discussed in depth in this case report.

Schlüsselwörter

chronische Inflammation - vaskuläre Risikofaktoren - Poststroke-Mania - Sekundäre Manien

Key words

chronic inflammation - vascular risk - poststroke mania - secondary mania
 

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