Whole Blood Polymerase Chain Reaction in a Neonate with Disseminated Herpes Simplex Virus Infection and Liver Failure

Jennifer A. Scoble; Mark A. Underwood

doi:10.1055/s-0033-1338167

American Journal of Perinatology Reports, Table of Contents

AJP Rep 2013; 03(02): 067-070
DOI: 10.1055/s-0033-1338167

Case Report

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Whole Blood Polymerase Chain Reaction in a Neonate with Disseminated Herpes Simplex Virus Infection and Liver Failure

Jennifer A. Scoble

¹Department of Pediatrics, University of California Davis, Sacramento, California

,

Mark A. Underwood

¹Department of Pediatrics, University of California Davis, Sacramento, California

› Author Affiliations

Abstract

A late preterm neonate born by cesarean section with intact membranes presented at 9 days of life with shock and liver failure. Surface cultures were negative but whole blood polymerase chain reaction was positive for herpes simplex virus type 2, underscoring the value of this test in early diagnosis of perinatally acquired disseminated herpes simplex virus infection without skin lesions.

Keywords

herpes simplex virus - liver failure - PCR - neonate - disseminated

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References

References
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