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Synthesis 2013; 45(9): 1256-1260
DOI: 10.1055/s-0033-1338473
DOI: 10.1055/s-0033-1338473
paper
Peptidoyl Benzotriazolide-Mediated Acylation of Nitrile-Activated Methylene Groups
Further Information
Publication History
Received: 18 December 2012
Accepted after revision: 05 March 2013
Publication Date:
09 April 2013 (online)
Abstract
Peptidoyl benzotriazoles permit the acylation of active methylene groups of nitriles to provide CH-acylated nitrile enols from α-amino acids or from di- or tripeptides with no loss of chirality.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information
-
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