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Synthesis 2014; 46(09): 1211-1216
DOI: 10.1055/s-0033-1338597
DOI: 10.1055/s-0033-1338597
paper
Synthesis of Pyrrolo[3,2-b]carbazole Derivatives via Palladium-Catalyzed C–H Activation
Further Information
Publication History
Received: 12 December 2013
Accepted after revision: 22 January 2014
Publication Date:
05 March 2014 (online)
Abstract
A simple method for the synthesis of different pyrrolo[3,2-b]carbazole derivatives by the reaction of 3-(acetylamino)carbazoles with various symmetrical diaryl-substituted alkynes via palladium-catalyzed C–H activation is reported.
Key words
3-aminocarbazoles - palladium catalysis - pyrrolo[3,2-b]carbazoles - C–H activation - diarylacetylenesSupporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information
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- 11 The crystal data for compounds 3a, 3e and 3i have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication nos. CCDC 892569 (3a), 892570 (3e) and 892571 (3i). Copies of the data can be obtained free of charge on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK [Fax: +44(1223)336033; E-mail: deposit@ccdc.cam.ac.uk] or via www.ccdc.cam.ac.uk/data_request/cif. Compound 3a: C30H24N2O; unit cell parameters: a = 10.2471(14) Å, b = 11.6921(11) Å, c = 19.105(3) Å, β = 99.605(11)°, space group P21/c. Compound 3e: C30H23BrN2O; unit cell parameters: a = 6.6599(13) Å, b = 19.948(4) Å, c = 17.974(3) Å, β = 98.107(18)°, space group P21/n. Compound 3i: C30H22Cl2N2O; unit cell parameters: a = 8.3466(18) Å, b = 33.171(5) Å, c = 10.746(3) Å, β = 126.096(16)°, space group P21/c.