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Synlett 2013; 24(14): 1781-1784
DOI: 10.1055/s-0033-1339306
DOI: 10.1055/s-0033-1339306
letter
Sequential Oxidation–Prins Reaction Processes Induced by the Same Iron Salt: Direct Access to 2-Aryl-4-Chloro-Tetrahydropyrans from Benzyl Alcohols
Further Information
Publication History
Received: 03 May 2013
Accepted after revision: 03 June 2013
Publication Date:
18 July 2013 (online)
Abstract
A clay-supported iron(III) nitrate (Clayfen) was used as a stoichiometric reagent to first oxidize benzylic alcohols. The aldehydes thus obtained were converted in situ into tetrahydropyrans by way of a Prins cyclization induced by iron species already present in the media.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synlett.
- Supporting Information
-
References and Notes
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