Solvent- and Ligand-Free Palladium-Catalyzed Amination of Aryl Halides

Abstract

An environmentally friendly and economically favorable approach to the formation of C–N bonds is presented. The methodology is particularly interesting in that the reaction is realized under both solvent- and ligand-free conditions and involves the use of a low loading of a palladium catalyst dispersed with the reactants on a suitable solid support. The reaction proceeds rapidly under microwave irradiation.

Key words

arylation - amination - catalysis - solid-phase synthesis - green-chemistry - microwave

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