An efficient catalytic system for the Mizoroki–Heck cross-coupling reaction was developed based on the air- and heat-stable palladium(II) chloride–cryptand 22 complex. The complex is a highly active catalyst for coupling of aryl iodides, bromides, or chlorides with various olefins.
Key words
Heck reaction - cross-coupling - halides - olefins - cryptands - catalysis