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Synthesis 2014; 46(06): 771-780
DOI: 10.1055/s-0033-1340479
DOI: 10.1055/s-0033-1340479
paper
A Highly Efficient and Stereoselective Cycloaddition of Nitrones to N-Vinylpyrroles
Further Information
Publication History
Received: 02 October 2013
Accepted after revision: 29 November 2013
Publication Date:
07 February 2014 (online)
Abstract
1,3-Dipolar cycloadditions of a number of C-aryl, C-carbamoyl-, and C,C-bis(methoxycarbonyl)nitrones and substituted N-vinylpyrroles proceed with high efficiency and regioselectivity with the formation of only one isomeric substituted 5-(1H-pyrrol-1-yl)isoxazolidine cycloadduct.
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