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Synthesis 2014; 46(07): 933-942
DOI: 10.1055/s-0033-1340734
DOI: 10.1055/s-0033-1340734
paper
Palladium-Catalyzed Cross-Coupling between 8-Substituted 6-Thiophenylpurines and Boronic Acids
Further Information
Publication History
Received: 14.11. 2013
Accepted after revision: 12 January 2014
Publication Date:
11 February 2014 (online)
Abstract
A palladium(II)-catalyzed, copper(I)-mediated Liebeskind–Srogl cross-coupling for the C-6 arylation/alkenylation on purine scaffold is reported. Various boronic acids reacted readily with 8-substituted 6-thiophenylpurines.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information
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