Synergistic Stereoselective Organocatalysis with Indium(III) Salts

Abstract

The compatibility of indium(III) Lewis acids with water and amines allows their employment in synergistic and cooperative catalysis. Stereoselective organocatalytic S_N1-type reactions, in which carbenium ions are generated, are promoted by the presence of indium salts. The peculiar properties of indium salts can be exploited in organocatalysis for the design of water-compatible, benign, green processes. The development of such indium(III)-promoted organocatalytic procedures is the focus of our recent research, a summary of which is presented in this article.

Key words

organocatalysis - stereoselective - amine catalysis - ­enamine-mediated catalysis - indium(III)

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