Am J Perinatol 2014; 31(03): 187-194
DOI: 10.1055/s-0033-1343771
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Prenatal Detection of Fetal Growth Restriction in Newborns Classified as Small for Gestational Age: Correlates and Risk of Neonatal Morbidity

Suneet P. Chauhan
1   Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia
,
Hind Beydoun
2   Graduate Program in Public Health, Eastern Virginia Medical School, Norfolk, Virginia
,
Eugene Chang
3   Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, South Carolina
,
Adam T. Sandlin
4   Department of Obstetrics and Gynecology, University of Arkansas, Little Rock, Arkansas
,
Josh D. Dahlke
5   Department of Obstetrics and Gynecology, Brown University, Providence, Rhode Island
,
Elena Igwe
6   Department of Obstetrics and Gynecology, Temple University, Philadelphia, Pennsylvania
,
Everett F. Magann
4   Department of Obstetrics and Gynecology, University of Arkansas, Little Rock, Arkansas
,
Kristi R. Anderson
7   Department of Obstetrics and Gynecology, Naval Medical Center Portsmouth, Portsmouth, Virginia
,
Alfred Z. Abuhamad
1   Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia
,
Cande V. Ananth
8   Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York
9   Department of Epidemiology, Joseph L. Mailman School of Public Health, Columbia University, New York
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Weitere Informationen

Publikationsverlauf

10. Januar 2013

06. März 2013

Publikationsdatum:
16. April 2013 (online)

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Abstract

We examined the rate of detecting small for gestational age (SGA; birth weight < 10%) as intrauterine growth restriction (IUGR) prenatally at four centers and determined risks of composite neonatal morbidity (CNM) and mortality among detected versus undetected (no antenatal diagnosis of IUGR). A multicenter cohort study of 11,487 nonanomalous, singleton live births with sonographic exam before 22 weeks was performed. Of 11,487 births, 8% (n = 929) were SGA that met the inclusion criteria, with 25% of them being prenatally detected. The CNM among SGA births that were prenatally detected as IUGR was higher (23.3%) than undetected SGA (9.7%), but this difference was no longer significant following adjustments for confounding factors. Among preterm births (< 37 weeks), undetected SGA had significantly higher CNM (risk ratio [RR] 10.0, 95% confidence interval [CI] 6.3, 16.1) for deliveries at 24 to 33 weeks and RR 3.0, 95% CI 1.7, 5.4 for 34 to 36 weeks). In summary, only a quarter of SGA births were detected prenatally as IUGR and among preterm SGA, the CNM is significantly higher when SGA births are undetected as IUGR.

Presentation Information

Presented at Society of Maternal-Fetal Medicine, Dallas, Texas, United States, February 6 to 11, 2012.