Antiviral-Resistant Fulminant Herpes Hepatitis in Pregnancy

Christina A. Herrera; Kacey Y. Eichelberger; Nancy C. Chescheir

doi:10.1055/s-0033-1343791

American Journal of Perinatology Reports, Inhaltsverzeichnis

AJP Rep 2013; 03(02): 087-090
DOI: 10.1055/s-0033-1343791

Case Report

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Antiviral-Resistant Fulminant Herpes Hepatitis in Pregnancy

Autor*innen

Christina A. Herrera

¹Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina
Kacey Y. Eichelberger

²Division of Maternal Fetal Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina
Nancy C. Chescheir

²Division of Maternal Fetal Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina

Abstract

Fulminant herpes hepatitis with disseminated extrahepatic involvement in pregnancy is rare and carries a high mortality risk. Although acyclovir remains standard first-line therapy, effective management of acyclovir-resistant disseminated herpes simplex virus (HSV) in pregnancy remains elusive. We present a case of disseminated HSV resistant to both acyclovir and foscarnet, the first double-agent resistant case in pregnancy reported in the literature to date. In this case, therapeutic delivery was the ultimate treatment resulting in full recovery.

Keywords

herpes hepatitis - fulminant herpes - pregnancy herpes - disseminated herpes

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Referenzen

References
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