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Semin Thromb Hemost 2013; 39(05): 489-495
DOI: 10.1055/s-0033-1343889
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Arterial and Venous Thrombosis in Endocrine Diseases

Bregje van Zaane
1   Department of Internal Medicine, Slotervaartziekenhuis, Amsterdam, The Netherlands
2   Department of Vascular Medicine, Academic Medical Centre, Amsterdam, The Netherlands
,
Danka J. F. Stuijver
1   Department of Internal Medicine, Slotervaartziekenhuis, Amsterdam, The Netherlands
2   Department of Vascular Medicine, Academic Medical Centre, Amsterdam, The Netherlands
,
Alessandro Squizzato
3   Department of Clinical and Experimental Medicine, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese, Italy
,
Victor E. A. Gerdes
1   Department of Internal Medicine, Slotervaartziekenhuis, Amsterdam, The Netherlands
2   Department of Vascular Medicine, Academic Medical Centre, Amsterdam, The Netherlands
› Author Affiliations
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Publication History

Publication Date:
30 April 2013 (online)

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Abstract

Endocrine diseases have been associated with cardiovascular events. Both altered coagulation and fibrinolysis markers and thrombotic disorders have been described in several endocrine diseases. This review summarizes the evidence on the influence of thyroid diseases, cortisol excess and deficiency, pheochromocytoma, hyperparathyroidism, hyperaldosteronism, hyperprolactinemia, and growth hormone excess and deficiency; on parameters of hemostasis; and on arterial and venous thrombotic events. All these endocrine diseases do have, or may have, influence either on hemostasis or on the risk of thrombotic events. Future studies are needed to establish the clinical relevance of these associations.

Keywords

thrombosis - thyroid hormone - cortisol - parathyroid hormone - aldosterone - pheochromocytoma - hyperprolactinemia - growth hormone
 

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