Inhalative Anästhetika in der Intensivmedizin

Kernaussagen

• Die Einführung der inhalativen Anästhetika auf der Intensivstation eröffnet eine interessante, weitere Möglichkeit der Analgosedierung.

• Bislang belegen 12 randomisierte, kontrollierte Studien die Durchführbarkeit, Effektivität und Sicherheit der inhalativen Sedierung.

• Dass volatile Anästhetika durch Konditionierung eine Organprotektion bieten, ist durch viele Studien belegt.

• Ob der Einsatz der inhalativen Sedierung auch einen positiven Effekt auf das Outcome hat, müssen entsprechende Studien noch zeigen.

• Eine Sedierung mit volatilen Anästhetika ermöglicht durch kurze Aufwachzeiten eine umgehende neurologische Beurteilbarkeit der Patienten und eine vereinfachte Entwöhnung von der Beatmung.

• Seit 2010 wird die inhalative Sedierung mit volatilen Anästhetika in der S3-Leitlinie „Sedierung, Analgesie und Delirmanagement in der Intensivmedizin“ als Alternative zur i. v. Sedierung empfohlen.

• Literatur

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