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Intensivmedizin up2date 2013; 09(03): 205-216
DOI: 10.1055/s-0033-1344581
Allgemeine Prinzipien der Intensivmedizin
© Georg Thieme Verlag KG Stuttgart · New York

Invasive Pilzinfektionen

Andreas Uekötter
,
Peter Brinkrolf
,
Klaus Hahnenkamp
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Publikationsverlauf

Publikationsdatum:
14. August 2013 (online)

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Kernaussagen

  • Invasive Pilzinfektionen nehmen bei intensivmedizinisch therapierten Patienten zu.

  • Die Sterblichkeit ist trotz neuer antimykotischer Therapieoptionen hoch.

  • Besondere Bedeutung hat eine frühzeitige Diagnostik, zumal die Letalität bei verzögertem Therapiebeginn stark ansteigt.

  • Zur Therapie der invasiven Candidose sollte man leitlinienkonform Echinocandine als Mittel der Wahl einsetzen.

  • Da sich der definitive Erregernachweis oft schwierig gestaltet, sollte man bei kritisch kranken, hämodynamisch instabilen Patienten mit Risikofaktoren für eine invasive Pilzinfektion eine kalkulierte Therapie in Erwägung ziehen.

 

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