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J Neurol Surg A Cent Eur Neurosurg 2013; 74(S 01): e237-e238
DOI: 10.1055/s-0033-1345092
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Aspergillosis Sinusitis with Cranio-Orbital Spread in an Apparently Immunocompetent Patient

Navneet Singh
1   Department of Neurosurgery, Manchester Skull Base Unit, Greater Manchester Neurosciences Centre, Salford Royal Hospital, Manchester, United Kingdom
,
Adarsh Nadig
1   Department of Neurosurgery, Manchester Skull Base Unit, Greater Manchester Neurosciences Centre, Salford Royal Hospital, Manchester, United Kingdom
,
Piyali Pal
2   Department of Neuropathology, Manchester Skull Base Unit, Greater Manchester Neurosciences Centre, Salford Royal Hospital, Manchester, United Kingdom
,
Chinari P.K. Subudhi
3   Department of Microbiology, Manchester Skull Base Unit, Greater Manchester Neurosciences Centre, Salford Royal Hospital, Manchester, United Kingdom
,
Kanna Gnanalingham
1   Department of Neurosurgery, Manchester Skull Base Unit, Greater Manchester Neurosciences Centre, Salford Royal Hospital, Manchester, United Kingdom
› Author Affiliations
Further Information

Publication History

01 April 2012

11 February 2013

Publication Date:
01 August 2013 (online)

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Abstract

Intracranial fungal infections are unusual and typically described in immunocompromised hosts. The authors describe a rare case of an immunocompetent white man presenting with blindness after Aspergillus fumigatus infection of the ethmoidal air sinus with spread to the orbital apex and the frontal lobe. This was successfully treated by surgical drainage via a frontal craniotomy and long-term antifungal therapy with voriconazole.

Keywords

cerebral aspergillosis - intracranial abscess - blindness - immunocompetent
 

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