Alienusolin, a New 4α-Deoxyphorbol Ester Derivative, and
                    Crotonimide C, a New Glutarimide Alkaloid from the Kenyan Croton
                    alienus

Beth Ndunda; Moses K. Langat; John M. Wanjohi; Jacob O. Midiwo; Leonidah O. Kerubo

doi:10.1055/s-0033-1351044

Planta Medica, Inhaltsverzeichnis

Planta Med 2013; 79(18): 1762-1766
DOI: 10.1055/s-0033-1351044

Natural Product Chemistry

Original Papers

Georg Thieme Verlag KG Stuttgart · New York

Alienusolin, a New 4α-Deoxyphorbol Ester Derivative, and Crotonimide C, a New Glutarimide Alkaloid from the Kenyan Croton alienus

Beth Ndunda

¹Department of Chemistry, Nairobi University, Nairobi, Kenya

,

Moses K. Langat

²Department of Chemistry, FEPS, University of Surrey, Guildford, Surrey, United Kingdom

,

John M. Wanjohi

¹Department of Chemistry, Nairobi University, Nairobi, Kenya

,

Jacob O. Midiwo

¹Department of Chemistry, Nairobi University, Nairobi, Kenya

,

Leonidah O. Kerubo

¹Department of Chemistry, Nairobi University, Nairobi, Kenya

› Institutsangaben

Abstract

Two novel compounds, alienusolin, a 4α-deoxyphorbol ester (1), crotonimide C, a glutarimide alkaloid derivative (2), and ten known compounds, julocrotine (3), crotepoxide (4), monodeacetyl crotepoxide (5), dideacetylcrotepoxide, (6), β-senepoxide (7), α-senepoxide (8), (+)-(2S,3R-diacetoxy-1-benzoyloxymethylenecyclohex-4,6-diene (9), benzyl benzoate (10), acetyl aleuritolic (11), and 24-ethylcholesta-4,22-dien-3-one (12) were isolated from the Kenyan Croton alienus. The structures of the compounds were determined using NMR, GCMS, and HRESIMS studies.

Key words

4α-deoxyphorbol ester - glutarimide alkaloid - Croton alienus - Euphorbiaceae

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Referenzen

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