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Planta Med 2013; 79(18): 1720-1723
DOI: 10.1055/s-0033-1351053
Natural Product Chemistry
Original Papers
Georg Thieme Verlag KG Stuttgart · New York

Further Lignans from Saururus chinensis

Xiu Gao
1   State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming, Peopleʼs Republic of China
2   University of Chinese Academy of Sciences, Beijing, Peopleʼs Republic of China
,
Juan He
1   State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming, Peopleʼs Republic of China
,
Xing-De Wu
1   State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming, Peopleʼs Republic of China
,
Li-Yan Peng
1   State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming, Peopleʼs Republic of China
,
Liao-Bin Dong
1   State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming, Peopleʼs Republic of China
2   University of Chinese Academy of Sciences, Beijing, Peopleʼs Republic of China
,
Xu Deng
1   State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming, Peopleʼs Republic of China
,
Yan Li
1   State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming, Peopleʼs Republic of China
,
Xiao Cheng
1   State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming, Peopleʼs Republic of China
,
Qin-Shi Zhao
1   State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming, Peopleʼs Republic of China
› Author Affiliations
Further Information

Publication History

received 17 April 2013
revised 24 July 2013

accepted 13 October 2013

Publication Date:
19 December 2013 (online)

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Abstract

Three new sauchinone analogues, sauchinones B–D (1–3), together with sauchinone (4), were isolated from the aerial part of Saururus chinensis. Structures of the new compounds were determined by extensive spectroscopic data as well as X-ray analysis. Compounds 3 and 4 inhibited nitric oxide production in lipopolysaccharide stimulated RAW 264.7 cells with IC50 values of 13.0 and 14.2 µM, respectively.

Key words

Saururus chinensis - Saururaceae - lignans - anti-inflammatory

Supporting Information

 

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