Evid Based Spine Care J 2013; 04(02): 096-104
DOI: 10.1055/s-0033-1357360
Systematic Review
Georg Thieme Verlag KG Stuttgart · New York

Outcomes in Adult Scoliosis Patients Who Undergo Spinal Fusion Stopping at L5 Compared with Extension to the Sacrum

Zeeshan M. Sardar
1   McGill Scoliosis and Spine Centre, McGill University Health Centre, Montreal, Quebec, Canada
,
Jean A. Ouellet
1   McGill Scoliosis and Spine Centre, McGill University Health Centre, Montreal, Quebec, Canada
,
Dena J. Fischer
2   Spectrum Research, Inc., Tacoma, Washington, United States
,
Andrea C. Skelly
2   Spectrum Research, Inc., Tacoma, Washington, United States
› Author Affiliations
Further Information

Publication History

15 May 2013

18 July 2013

Publication Date:
21 November 2013 (online)

Abstract

Study Design Systematic review.

Study Rationale Adult scoliosis is a common disorder that is associated with significantly higher pain, functional impairment, and effect on quality of life than those without scoliosis. Surgical spinal fusion has led to quantifiable improvement in patient's quality of life. However, for patients undergoing long lumbar fusion, the decision to stop the fusion at L5 or to extend to S1, particularly if the L5–S1 disc is healthy, remains controversial.

Objective The aim of the study is to evaluate if fusion stopping at L5 increases the comparative rates of revision, correction loss, and/or poor functional outcomes compared with extension to the sacrum in adult scoliosis patients who require spinal fusion surgery.

Materials and Methods A systematic review of the literature was performed using PubMed, the National Guideline Clearinghouse Database and bibliographies of key articles that evaluated adult scoliosis patients who required spinal fusion surgery and compared outcomes for fusions to the sacrum versus stopping at L5. Articles were included on the basis of predetermined criteria and were appraised using a predefined quality-rating scheme.

Results From 111 citations, 26 articles underwent full-text review, and 3 retrospective cohort studies met all inclusion and exclusion criteria. Revision rates in subjects who underwent spinal fusion to L5 (20.8–23.5%) were lower in two studies compared with those with fusion extending to the sacrum (19.0–58.3%). Studies that assessed deformity correction used different measures, making comparison across studies difficult. No significant differences were found in patient-reported functional outcomes across two studies that used different measures.

Conclusion The limited data available suggest that differences in revision rates did not consistently reach statistical significance across studies that compared spinal fusion to L5 versus extension to sacrum in adult scoliosis patients.

Supplementary Material

 
  • References

  • 1 Kilshaw M, Baker RP, Gardner R, Charosky S, Harding I. Abnormalities of the lumbar spine in the coronal plane on plain abdominal radiographs. Eur Spine J 2011; 20 (3) 429-433
  • 2 Schwab F, el-Fegoun AB, Gamez L, Goodman H, Farcy JP. A lumbar classification of scoliosis in the adult patient: preliminary approach. Spine (Phila Pa 1976) 2005; 30 (14) 1670-1673
  • 3 Cho KJ, Suk SI, Park SR , et al. Arthrodesis to L5 versus S1 in long instrumentation and fusion for degenerative lumbar scoliosis. Eur Spine J 2009; 18 (4) 531-537
  • 4 Ohtori S, Sainoh T, Takaso M , et al. Clinical incidence of sacroiliac joint arthritis and pain after sacropelvic fixation for spinal deformity. Yonsei Med J 2012; 53 (2) 416-421
  • 5 Urrutia J, Espinosa J, Diaz-Ledezma C, Cabello C. The impact of lumbar scoliosis on pain, function and health-related quality of life in postmenopausal women. Eur Spine J 2011; 20 (12) 2223-2227
  • 6 Kebaish KM, Neubauer PR, Voros GD, Khoshnevisan MA, Skolasky RL. Scoliosis in adults aged forty years and older: prevalence and relationship to age, race, and gender. Spine (Phila Pa 1976) 2011; 36 (9) 731-736
  • 7 Kim YJ, Bridwell KH, Lenke LG, Rhim S, Cheh G. Sagittal thoracic decompensation following long adult lumbar spinal instrumentation and fusion to L5 or S1: causes, prevalence, and risk factor analysis. Spine (Phila Pa 1976) 2006; 31 (20) 2359-2366
  • 8 Emami A, Deviren V, Berven S, Smith JA, Hu SS, Bradford DS. Outcome and complications of long fusions to the sacrum in adult spine deformity: luque-galveston, combined iliac and sacral screws, and sacral fixation. Spine (Phila Pa 1976) 2002; 27 (7) 776-786
  • 9 Kostuik JP, Hall BB. Spinal fusions to the sacrum in adults with scoliosis. Spine (Phila Pa 1976) 1983; 8 (5) 489-500
  • 10 Kuhns CA, Bridwell KH, Lenke LG , et al. Thoracolumbar deformity arthrodesis stopping at L5: fate of the L5-S1 disc, minimum 5-year follow-up. Spine (Phila Pa 1976) 2007; 32 (24) 2771-2776
  • 11 Weistroffer JK, Perra JH, Lonstein JE , et al. Complications in long fusions to the sacrum for adult scoliosis: minimum five-year analysis of fifty patients. Spine (Phila Pa 1976) 2008; 33 (13) 1478-1483
  • 12 Wright JG, Swiontkowski MF, Heckman JD. Introducing levels of evidence to the journal. J Bone Joint Surg Am 2003; 85-A (1) 1-3
  • 13 Methods Guide for Effectiveness and Comparative Effectiveness Reviews. Rockville, MD: Agency for Healthcare Research and Quality; 2012
  • 14 West S, King V, Carey TS , et al. Systems to Rate the Strength of Scientific Evidence. Evidence Report/Technology Assessment No. 47 (Prepared by the Research Triangle Institute-University of North Carolina Evidence-based Practice Center, Contract No. 290–97–0011). Rockville, MD: Agency for Healthcare Research and Quality; 2002
  • 15 Atkins D, Best D, Briss PA , et al; GRADE Working Group. Grading quality of evidence and strength of recommendations. BMJ 2004; 328 (7454) 1490
  • 16 Mok JM, Cloyd JM, Bradford DS , et al. Reoperation after primary fusion for adult spinal deformity: rate, reason, and timing. Spine (Phila Pa 1976) 2009; 34 (8) 832-839
  • 17 Edwards II CC, Bridwell KH, Patel A, Rinella AS, Berra A, Lenke LG. Long adult deformity fusions to L5 and the sacrum. A matched cohort analysis. Spine (Phila Pa 1976) 2004; 29 (18) 1996-2005