Dtsch Med Wochenschr 2013; 138(49): 2509-2511
DOI: 10.1055/s-0033-1359869
Endokrinologie & Diabetologie | Commentary
Endokrinologie
© Georg Thieme Verlag KG Stuttgart · New York

Hyperandrogenämie

Hyperandrogenemia
M. Haase
1   Klinik für Endokrinologie und Diabetologie, Medizinische Fakultät Düsseldorf, Universitätsklinikum Düsseldorf
2   Medizinische Klinik und Poliklinik III, Universitätsklinikum Carl Gustav Carus der Technischen Universität Dresden
,
H. S. Willenberg
1   Klinik für Endokrinologie und Diabetologie, Medizinische Fakultät Düsseldorf, Universitätsklinikum Düsseldorf
2   Medizinische Klinik und Poliklinik III, Universitätsklinikum Carl Gustav Carus der Technischen Universität Dresden
› Author Affiliations
Further Information

Publication History

Publication Date:
26 November 2013 (online)

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Schlüsselwörter

Hyperandrogenämie - Testosteron - polyzystisches Ovarsysndrom - adrenogenitales Syndrom

Keywords

hyperandrogenemia - testosterone - polycystic ovary syndrome - adrenogenital syndrome
 

  • Literatur

  • 1 Arlt W, Biehl M, Taylor AE et al. Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors. J Clin Endocrinol Metab 2011; 96: 3775-3784
    CrossrefGoogle Scholar
  • 2 Auchus RJ, Arlt W. Approach to the patient: the adult with congenital adrenal hyperplasia. J Clin Endocrinol Metab 2013; 98: 2645-2655
    CrossrefPubMedGoogle Scholar
  • 3 Azziz R, Carmina E, Dewailly D et al. The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril 2009; 91: 456-88
    CrossrefPubMedGoogle Scholar
  • 4 Boot AM, Lumbroso S, Verhoef-Post M et al. Mutation analysis of the LH receptor gene in Leydig cell adenoma and hyperplasia and functional and biochemical studies of activating mutations of the LH receptor gene. J Clin Endocrinol Metab 2011; 96: E1197-205
    CrossrefGoogle Scholar
  • 5 Chan AO, Shek CC. Urinary steroid profiling in the diagnosis of congenital adrenal hyperplasia and disorders of sex development: experience of a urinary steroid referral centre in Hong Kong. Clin Biochem 2013; 46: 327-334
    CrossrefGoogle Scholar
  • 6 Costa-Barbosa FA, Carvalho VM, Nakamura OH et al. Zona fasciculata 21-hydroxysteroids and precursor-to-product ratios in 21-hydroxylase deficiency: further characterization of classic and non-classic patients and heterozygote carriers. J Endocrinol Invest 2011; 34: 587-592
    Google Scholar
  • 7 Costa-Barbosa FA, Tonetto-Fernandes VF, Carvalho VM et al. Superior discriminating value of ACTH-stimulated serum 21-deoxycortisol in identifying heterozygote carriers for 21-hydroxylase deficiency. Clin Endocrinol 2010; 73: 700-706
    CrossrefGoogle Scholar
  • 8 Domecq JP, Prutsky G, Mullan RJ et al. Adverse effects of the common treatments for polycystic ovary syndrome. J Clin Endocrinol Metab 2013; Oct 3. Epub ahead of print
    Google Scholar
  • 9 Domecq JP, Prutsky G, Mullan RJ et al. Lifestyle modification programs in polycystic ovary syndrome. J Clin Endocrinol Metab 2013; Oct 3. Epub ahead of print
    Google Scholar
  • 10 Ganie MA, Khurana ML, Nisar S et al. Improved efficacy of low-dose spironolactone and metformin combination than either drug alone in the management of women with polycystic ovary syndrome (PCOS). J Clin Endocrinol Metab 2013; 98: 3599-3607
    CrossrefPubMedGoogle Scholar
  • 11 Han TS, Stimson RH, Rees DA et al. United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE). Glucocorticoid treatment regimen and health outcomes in adults with congenital adrenal hyperplasia. Clin Endocrinol 2013; 78: 197-203
    CrossrefGoogle Scholar
  • 12 Handelsman DJ, Wartofsky L. Requirement for mass spectrometry sex steroid assays in the Journal of Clinical Endocrinology and Metabolism. J Clin Endocrinol Metab 2013; 98: 3971-3973
    CrossrefGoogle Scholar
  • 13 Johannsson G, Nilsson AG, Bergthorsdottir R et al. Improved cortisol exposure-time profile and outcome in patients with adrenal insufficiency. J Clin Endocrinol Metab 2012; 97: 473-481
    CrossrefGoogle Scholar
  • 14 Koulouri O, Conway GS. A systematic review of commonly used medical treatments for hirsutism in women. Clin Endocrinol 2008; 68: 800-805
    CrossrefGoogle Scholar
  • 15 Levens ED, Whitcomb BW, Csokmay JM et al. Selective venous sampling for androgen-producing ovarian pathology. Clin Endocrinol 2009; 70: 606-614
    CrossrefGoogle Scholar
  • 16 New MI, Abraham M, Gonzalez B et al. Genotype-phenotype correlation in 1,507 families with congenital adrenal hyperplasia owing to 21-hydroxylase deficiency. Proc Natl Acad Sci U S A 2013; 110: 2611-2616
    CrossrefGoogle Scholar
  • 17 Nieman LK, Biller BM, Findling JW et al. The diagnosis of Cushing's syndrome. J Clin Endocrinol Metab 2008; 93: 1526-1540
    Google Scholar
  • 18 NIH Office of Disease Prevention. Evidence-based Methodology Workshop on PCOS December 2012. http://prevention.nih.gov/workshops/2012/pcos/resources.aspx (letzter Zugriff 22.10.2013).
    Google Scholar
  • 19 Speiser PW, Azziz R, Baskin LS et al. Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency. J Clin Endocrinol Metab 2010; 95: 4133-60 Erratum in: J Clin Endocrinol Metab. 2010; 95: 5137
    CrossrefPubMedGoogle Scholar
  • 20 Zimmerman Y, Eijkemans MJ, Coelingh Bennink HJ et al. The effect of combined oral contraception on testosterone levels in healthy women. Hum Reprod Update 2013; Epub ahead of print
    Google Scholar