Download PDF
Int J Sports Med 2014; 35(11): 894-899
DOI: 10.1055/s-0033-1363266
Physiology & Biochemistry
© Georg Thieme Verlag KG Stuttgart · New York

Effect of a Single Bout of Resistance Exercise on Arterial Stiffness Following a High-Fat Meal

J. Augustine
1   Exercise Science, Syracuse University, Syracuse, United States
,
B. Tarzia
1   Exercise Science, Syracuse University, Syracuse, United States
,
A. Kasprowicz
1   Exercise Science, Syracuse University, Syracuse, United States
,
K. S. Heffernan
2   Department of Exercise Science, Syracuse University, Syracuse, United States
› Author Affiliations
Further Information

Publication History



accepted after revision 19 November 2013

Publication Date:
02 June 2014 (online)

Also available at
    Permissions and Reprints

Abstract

Consumption of a high-fat meal (HFM) causes postprandial lipemia and vascular dysfunction. Acute resistance exercise (RE) alone may also have a negative effect on vascular function. The purpose of this study was to measure arterial stiffness and postprandial lipemia after a HFM with or without acute RE. 9 recreationally active men (age 24±5 years, BMI 25±3 kg/m2) completed both: (1) HFM alone and (2) HFM+RE in a randomized order. Pulse wave velocity (PWV) from carotid to femoral artery and carotid to radial artery were used as measures of central/aortic and peripheral arterial stiffness, respectively. Circulating triglycerides (TRG) were obtained from finger stick samples as a marker of lipemia. There was a significant condition-by-time interaction for TRG (p<0.05). TRG levels increased significantly following both conditions with a significantly attenuated increase following HFM+RE (p<0.05). There was a significant condition-by-time interaction for peripheral PWV as this parameter increased following HFM, but decreased following HFM+RE (p=0.021). Central PWV did not change with HFM or HFM+RE (p>0.05). Following a HFM, acute RE attenuates postprandial lipemia and improves peripheral arterial stiffness without having a negative effect on central arterial stiffness.

Key words

vascular function - arterial stiffness - high-fat meal - resistance exercise
 

  • References

  • 1 Baechle TR, Earle RW. Essentials of Strength Training and Conditioning. Champaign, IL: Human Kinetics; 2008
    Search in Google Scholar
  • 2 Bellien J, Favre J, Iacob M, Gao J, Thuillez C, Richard V, Joannides R. Arterial stiffness is regulated by nitric oxide and endothelium-derived hyperpolarizing factor during changes in blood flow in humans. Hypertension 2010; 55: 674-680
    CrossrefPubMedSearch in Google Scholar
  • 3 Blendea MC, Bard M, Sowers JR, Winer N. High-fat meal impairs vascular compliance in a subgroup of young healthy subjects. Metabolism 2005; 54: 1337-1344
    CrossrefPubMedSearch in Google Scholar
  • 4 Bloomer RJ, Fisher-Wellman KH. Lower postprandial oxidative stress in women compared with men. Gend Med 2010; 7: 340-349
    CrossrefPubMedSearch in Google Scholar
  • 5 Burns SF, Broom DR, Miyashita M, Ueda C, Stensel DJ. Increased postprandial triacylglycerol concentrations following resistance exercise. Med Sci Sports Exerc 2006; 38: 527-533
    CrossrefPubMedSearch in Google Scholar
  • 6 Clegg M, McClean C, Davison WG, Murphy HM, Trinick T, Duly E, McLaughlin J, Fogarty M, Shafat A. Exercise and postprandial lipaemia: effects on peripheral vascular function, oxidative stress and gastrointestinal transit. Lipids Health Dis 2007; 6: 30
    CrossrefPubMedSearch in Google Scholar
  • 7 DeVan AE, Anton MM, Cook JN, Neidre DB, Cortez-Cooper MY, Tanaka H. Acute effects of resistance exercise on arterial compliance. J Appl Physiol 2005; 98: 2287-2291
    CrossrefPubMedSearch in Google Scholar
  • 8 Eriksen M, Waaler BA. Priority of blood flow to splanchnic organs in humans during pre- and post-meal exercise. Acta Physiol Scand 1994; 150: 363-372
    CrossrefPubMedSearch in Google Scholar
  • 9 Fahs CA, Heffernan KS, Fernhall B. Hemodynamic and vascular response to resistance exercise with L-arginine. Med Sci Sports Exerc 2009; 41: 773-779
    CrossrefPubMedSearch in Google Scholar
  • 10 Fahs CA, Yan H, Ranadive S, Rossow LM, Agiovlasitis S, Wilund KR, Fernhall B. The effect of acute fish-oil supplementation on endothelial function and arterial stiffness following a high-fat meal. Appl Physiol Nutr Metab 2010; 35: 294-302
    CrossrefPubMedSearch in Google Scholar
  • 11 Gill JM, Al-Mamari A, Ferrell WR, Cleland SJ, Packard CJ, Sattar N, Petrie JR, Caslake MJ. Effects of prior moderate exercise on postprandial metabolism and vascular function in lean and centrally obese men. J Am Coll Cardiol 2004; 44: 2375-2382
    CrossrefPubMedSearch in Google Scholar
  • 12 Goto C, Nishioka K, Umemura T, Jitsuiki D, Sakagutchi A, Kawamura M, Chayama K, Yoshizumi M, Higashi Y. Acute moderate-intensity exercise induces vasodilation through an increase in nitric oxide bioavailiability in humans. Am J Hypertens 2007; 20: 825-830
    CrossrefPubMedSearch in Google Scholar
  • 13 Harris RA, Tedjasaputra V, Zhao J, Richardson RS. Premenopausal women exhibit an inherent protection of endothelial function following a high-fat meal. Reprod Sci 2012; 19: 221-228
    CrossrefPubMedSearch in Google Scholar
  • 14 Harriss DJ, Atkinson G. 2014 Update – Ethical standards in sport and exercise science research. Int J Sports Med 2013; 34: 1025-1028
    Thieme ConnectPubMedSearch in Google Scholar
  • 15 Heffernan KS, Collier SR, Kelly EE, Jae SY, Fernhall B. Arterial stiffness and baroreflex sensitivity following bouts of aerobic and resistance exercise. Int J Sports Med 2007; 28: 197-203
    Thieme ConnectPubMedSearch in Google Scholar
  • 16 Heffernan KS, Jae SY, Edwards DG, Kelly EE, Fernhall B. Arterial stiffness following repeated Valsalva maneuvers and resistance exercise in young men. Appl Physiol Nutr Metab 2007; 32: 257-264
    CrossrefPubMedSearch in Google Scholar
  • 17 Jurva JW, Phillips SA, Syed AQ, Syed AY, Pitt S, Weaver A, Gutterman DD. The effect of exertional hypertension evoked by weight lifting on vascular endothelial function. J Am Coll Cardiol 2006; 48: 588-589
    CrossrefPubMedSearch in Google Scholar
  • 18 Kingwell BA, Berry KL, Cameron JD, Jennings GL, Dart AM. Arterial compliance increases after moderate-intensity cycling. Am J Physiol 1997; 273: H2186-H2191
    PubMedSearch in Google Scholar
  • 19 Kinlay S, Creager MA, Fukumoto M, Hikita H, Fang JC, Selwyn AP, Ganz P. Endothelium-derived nitric oxide regulates arterial elasticity in human arteries in vivo. Hypertension 2001; 38: 1049-1053
    CrossrefPubMedSearch in Google Scholar
  • 20 Knuth ND, Horowitz JF. The elevation of ingested lipids within plasma chylomicrons is prolonged in men compared with women. J Nutr 2006; 136: 1498-1503
    PubMedSearch in Google Scholar
  • 21 Lithander FE, Herlihy LK, Walsh DM, Burke E, Crowley V, Mahmud A. Postprandial effect of dietary fat quantity and quality on arterial stiffness and wave reflection: a randomised controlled trial. Nutr J 2013; 12: 93
    CrossrefPubMedSearch in Google Scholar
  • 22 Mc Clean CM, Mc Laughlin J, Burke G, Murphy MH, Trinick T, Duly E, Davison GW. The effect of acute aerobic exercise on pulse wave velocity and oxidative stress following postprandial hypertriglyceridemia in healthy men. Eur J Appl Physiol 2007; 100: 225-234
    CrossrefPubMedSearch in Google Scholar
  • 23 Naka KK, Tweddel AC, Doshi SN, Goodfellow J, Henderson AH. Flow-mediated changes in pulse wave velocity: a new clinical measure of endothelial function. Eur Heart J 2006; 27: 302-309
    PubMedSearch in Google Scholar
  • 24 Nestel PJ, Shige H, Pomeroy S, Cehun M, Chin-Dusting J. Post-prandial remnant lipids impair arterial compliance. J Am Coll Cardiol 2001; 37: 1929-1935
    CrossrefPubMedSearch in Google Scholar
  • 25 Nordestgaard BG, Benn M, Schnohr P, Tybjaerg-Hansen A. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 2007; 298: 299-308
    CrossrefPubMedSearch in Google Scholar
  • 26 Padilla J, Harris RA, Fly AD, Rink LD, Wallace JP. The effect of acute exercise on endothelial function following a high-fat meal. Eur J Appl Physiol 2006; 98: 256-262
    CrossrefPubMedSearch in Google Scholar
  • 27 Perko MJ, Nielsen HB, Skak C, Clemmesen JO, Schroeder TV, Secher NH. Mesenteric, coeliac and splanchnic blood flow in humans during exercise. J Physiol 1998; 513 (Pt 3) 907-913
    CrossrefPubMedSearch in Google Scholar
  • 28 Petitt DS, Arngrimsson SA, Cureton KJ. Effect of resistance exercise on postprandial lipemia. J Appl Physiol 2003; 94: 694-700
    CrossrefPubMedSearch in Google Scholar
  • 29 Robertson MD, Jackson KG, Fielding BA, Williams CM, Frayn KN. Acute effects of meal fatty acid composition on insulin sensitivity in healthy post-menopausal women. Br J Nutr 2002; 88: 635-640
    CrossrefPubMedSearch in Google Scholar
  • 30 Rontoyanni VG, Chowienczyk PJ, Sanders TA. Postprandial lipaemia does not affect resting haemodynamic responses but does influence cardiovascular reactivity to dynamic exercise. Br J Nutr 2010; 104: 863-871
    CrossrefPubMedSearch in Google Scholar
  • 31 Santee J. Accuracy and precision of the Cholestech LDX System in monitoring blood lipid levels. Am J Health Syst Pharm 2002; 59: 1774-1779
    PubMedSearch in Google Scholar
  • 32 Shannon KA, Shannon RM, Clore JN, Gennings C, Warren BJ, Potteiger JA. Resistance exercise and postprandial lipemia: The dose effect of differing volumes of acute resistance exercise bouts. Metabolism 2005; 54: 756-763
    CrossrefPubMedSearch in Google Scholar
  • 33 Sidery MB, Macdonald IA, Blackshaw PE. Superior mesenteric artery blood flow and gastric emptying in humans and the differential effects of high fat and high carbohydrate meals. Gut 1994; 35: 186-190
    CrossrefPubMedSearch in Google Scholar
  • 34 Singhal A, Trilk JL, Jenkins NT, Bigelman KA, Cureton KJ. Effect of intensity of resistance exercise on postprandial lipemia. J Appl Physiol 2009; 106: 823-829
    CrossrefPubMedSearch in Google Scholar
  • 35 Steinberg HO, Brechtel G, Johnson A, Fineberg N, Baron AD. Insulin-mediated skeletal muscle vasodilation is nitric oxide-dependent. A novel action of insulin to increase nitric oxide release. J Clin Invest 1994; 94: 1172-1179
    CrossrefPubMedSearch in Google Scholar
  • 36 Sugawara J, Maeda S, Otsuki T, Tanabe T, Ajisaka R, Matsuda M. Effects of nitric oxide synthase inhibitor on decrease in peripheral arterial stiffness with acute low-intensity aerobic exercise. Am J Physiol Heart Circ Physiol 2004; 287: H2666-H2669
    CrossrefPubMedSearch in Google Scholar
  • 37 Tentor J, Harada LM, Nakamura RT, Gidlund M, Castilho LN. Cotta de Faria E Sex-dependent variables in the modulation of postalimentary lipemia. Nutrition 2006; 22: 9-15
    CrossrefPubMedSearch in Google Scholar
  • 38 Tushuizen ME, Nieuwland R, Scheffer PG, Sturk A, Heine RJ, Diamant M. Two consecutive high-fat meals affect endothelial-dependent vasodilation, oxidative stress and cellular microparticles in healthy men. J Thromb Haemost 2006; 4: 1003-1010
    CrossrefPubMedSearch in Google Scholar
  • 39 Waaler BA, Toska K, Eriksen M. Involvement of the human splanchnic circulation in pressor response induced by handgrip contraction. Acta Physiol Scand 1999; 166: 131-136
    CrossrefPubMedSearch in Google Scholar
  • 40 Wallace JP, Johnson B, Padilla J, Mather K. Postprandial lipaemia, oxidative stress and endothelial function: a review. Int J Clin Pract 2010; 64: 389-403
    CrossrefPubMedSearch in Google Scholar
  • 41 Westerbacka J, Wilkinson I, Cockcroft J, Utriainen T, Vehkavaara S, Yki-Jarvinen H. Diminished wave reflection in the aorta. A novel physiological action of insulin on large blood vessels. Hypertension 1999; 33: 1118-1122
    CrossrefPubMedSearch in Google Scholar
  • 42 Yoon ES, Jung SJ, Cheun SK, Oh YS, Kim SH, Jae SY. Effects of acute resistance exercise on arterial stiffness in young men. Korean Circ J 2010; 40: 16-22
    CrossrefPubMedSearch in Google Scholar
  • 43 Zafeiridis A, Goloi E, Petridou A, Dipla K, Mougios V, Kellis S. Effects of low- and high-volume resistance exercise on postprandial lipaemia. Br J Nutr 2007; 97: 471-477
    CrossrefPubMedSearch in Google Scholar