Autoinflammatory Diseases (AID)

G. Dueckers; O. Sander; T. Niehues

doi:10.1055/s-0034-1366987

Klinische Pädiatrie, Table of Contents

Klin Padiatr 2014; 226(03): 133-142
DOI: 10.1055/s-0034-1366987

Review

Autoinflammatory Diseases (AID)

Autoinflammatorische Erkrankungen

G. Dueckers

¹Childrens Hospital, HELIOS Klinikum Krefeld, Krefeld, Germany

,

O. Sander

²Department for Rheumatology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany

,

T. Niehues

¹Childrens Hospital, HELIOS Klinikum Krefeld, Krefeld, Germany

› Author Affiliations

Abstract

Most of the autoinflammatory diseases (AID) are orphan diseases with recurrent episodes of systemic inflammation. Fever and exanthema are leading features. Given the ongoing elucidation of pathogenic causes and hence therapeutic approaches, we provided a review of the current literature of AID.

Zusammenfassung

Die meisten autoinflammatorischen Erkrankungen sind seltene Erkrankungen mit wiederkehrenden Episoden systemischer Inflammation. Fieber und Exanthem sind führende Merkmale. In Anbetracht der fortlaufenden Aufklärung pathogenetischer Ursachen und der daraus resultierenden Therapieansätze, stellen wir die gegenwärtige Literatur über AID zusammenfassend dar.

Key words

autoinflammatory diseases - monogenetic - inflammasome - interleukin 1

Schlüsselwörter

Autoinflammation - monogenetische Erkrankungen - Inflammasom - Interleukin 1

Full Text

References

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