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Int J Sports Med 2014; 35(10): 863-870
DOI: 10.1055/s-0034-1367045
Genetics & Molecular Biology
© Georg Thieme Verlag KG Stuttgart · New York

Futsal and Continuous Exercise Induce Similar Changes in Specific Skeletal Muscle Signalling Proteins

F. R. Serpiello
1   Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University, Melbourne, Australia
,
M. J. McKenna
1   Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University, Melbourne, Australia
,
G. Coratella
2   Department of Neurological, Neuropsychological, Morphological and ­Movement Sciences, Faculty of Sport Sciences, University of Verona, Italy
,
J. F. Markworth
3   The University of Auckland, Liggins Institute, Auckland, New Zealand
,
C. Tarperi
2   Department of Neurological, Neuropsychological, Morphological and ­Movement Sciences, Faculty of Sport Sciences, University of Verona, Italy
,
D. Bishop
1   Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University, Melbourne, Australia
,
N. K. Stepto
1   Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University, Melbourne, Australia
,
D. Cameron-Smith
3   The University of Auckland, Liggins Institute, Auckland, New Zealand
,
F. Schena
2   Department of Neurological, Neuropsychological, Morphological and ­Movement Sciences, Faculty of Sport Sciences, University of Verona, Italy
› Author Affiliations
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Publication History



accepted after revision 19 December 2013

Publication Date:
27 February 2014 (online)

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Abstract

Exercise elicits skeletal-muscle adaptations which are important for improved health outcomes. We compared the effects of a futsal game (FUT) and moderate-intensity continuous exercise (MOD), on the skeletal-muscle protein signalling responses in young, healthy individuals. 16 men undertook an incremental exercise test and a resting muscle biopsy performed >48 h apart. They were then randomly allocated to either FUT (n=12) consisting of 2 x 20 min halves, or MOD (n=8) consisting of a work-matched running bout performed at an intensity corresponding to the individual ventilatory threshold 1. Work matching was achieved by means of triaxial accelerometers. Immediately after FUT and MOD, participants underwent a second biopsy to assess exercise-induced changes in protein signalling. Total and phosphorylated protein abundance was assessed via western blotting. Both FUT and MOD altered signalling responses in skeletal muscle. FUT increased total ATF2 protein abundance (p=0.048) and phosphorylation (p=0.029), while no changes occurred with MOD. Both exercise regimes increased ACC phosphorylation (p=0.01) and returned a trend for increased p38MAPK phosphorylation. Futsal may be employed as an alternative to continuous exercise to elicit muscle adaptations which may be associated with improved health outcomes. As only FUT increased ATF2 activation, this protein might be a target of future investigation on exercise-induced signalling.

Key words

intermittent exercise - protein signalling - ATF2 - football
 

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