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Exp Clin Endocrinol Diabetes 2014; 122(04): 208-214
DOI: 10.1055/s-0034-1367062
Review
© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Epidemiology of Cardiovascular Disease in Patients with Type 1 Diabetes: European Perspective

E. Matteucci
1   Department of Clinical and Experimental Medicine, University of Pisa, Italy
,
O. Giampietro
1   Department of Clinical and Experimental Medicine, University of Pisa, Italy
› Author Affiliations
Further Information

Publication History

received 22 November 2013
first decision 09 January 2014

accepted 22 January 2014

Publication Date:
25 April 2014 (online)

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Abstract

The International Diabetes Federation estimated that 5.1 million people aged between 20 and 79 years died from diabetes in 2013, accounting for 8.4% of global all-cause mortality among people in this age group. Type 1 diabetes is associated with a 2- to 4-fold increased mortality risk compared with the general population. Before the onset of late complications, most of the excess mortality is from potentially preventable causes of death such as ketoacidosis, whereas the long-term excess mortality is largely due to cardiovascular disease. However, a wide geographic variation in mortality of type 1 diabetic patients has been evidenced and accurate estimates of mortality attributable to diabetes are difficult to obtain. The review provides an overview of currently available evidence and summarizes main problems in estimating early and long-term mortality by cause of death in type 1 diabetes, paying particular attention to European studies.

Key words

diabetes mellitus type 1 - mortality - cardiovascular disease - Europe
 

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