Abstract
Introduction The presence of respiratory viruses in lymphoid tissues of the nasopharynx and oropharynx
and its impact on recurrent infections and hypertrophy of these tissues are not yet
fully understood.
Objective To identify and determine the prevalence of major respiratory viruses in nasopharyngeal
secretions and adenoid tissue pre- and postoperatively of children undergoing adenoidectomy.
Methods A prospective observational study was conducted in 36 patients under 12 years of
age with upper airway lymphoid hypertrophy who were undergoing adenoidectomy, in which
various respiratory viruses were investigated using real-time polymerase chain reaction
in adenoid tissue and nasopharyngeal secretions collected preoperatively and 30 days
postoperatively.
Results At least 1 viral agent was isolated in any of the samples collected in 58.3% of children
and 25.9% of total samples. Respiratory viruses were identified in 33.8% of preoperative
nasopharyngeal specimens and in 19.8% of postoperative secretion. Of the 21 patients
with positive results for any respiratory virus, 6 (28.6%) had more than 1 virus.
Considering all 36 respiratory viruses found, the main agent isolated was rhinovirus
(27.8%), followed by bocavirus (22.2%).
Conclusion The virus found more frequently in all samples was rhinovirus. After removal of adenoid
tissue, there was a decrease in the prevalence of the virus contained in nasopharyngeal
secretion 30 days after surgery.
Keywords
viruses - adenoids - adenoidectomy - child - polymerase chain reaction
