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Klinische Neurophysiologie 2014; 45(02): 85-93
DOI: 10.1055/s-0034-1370054
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© Georg Thieme Verlag KG Stuttgart · New York

Tremor: Pathophysiologische Konzepte und Ergebnisse der Tiefen Hirnstimulation

Tremor: Pathophysiological Concepts and Results of Deep Brain Stimulation
D. J. Pedrosa
1   Klinik und Poliklinik für Neurologie der Universitätsklinik zu Köln
,
J. Hirschmann
2   Klinische Neurowissenschaften und Medizinische Psychologie, Universitätsklinik Düsseldorf
,
M. T. Barbe
1   Klinik und Poliklinik für Neurologie der Universitätsklinik zu Köln
› Author Affiliations
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Publication History

Publication Date:
01 July 2014 (online)

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Kernaussagen

  • Tremor ist ein Netzwerkphänomen, zu dem insbesondere die zerebello-thalamo-kortikale und die Basalganglienschleife beitragen.

  • Tremor-Patienten zeigen eine pathologische Hypersynchronisation zwischen den Arealen des Tremornetzwerks.

  • Tremor kann durch Tiefe Hirnstimulation im VIM, STN oder GPi effizient reduziert werden.

  • Bei der Wahl des Zielpunkts sind neben dem Schweregrad des Tremors auch die weiteren Symptome und mögliche Nebenwirkungen in Betracht zu ziehen.

 

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