Download PDF
Semin Liver Dis 2014; 34(01): 089-097
DOI: 10.1055/s-0034-1371082
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Hepatitis C, A Global Issue: Access to Care and New Therapeutic and Preventive Approaches in Resource-Constrained Areas

Maud Lemoine
1   Hepatology & Gastroenterology Section, Imperial College, London, United Kingdom
,
Mark Thursz
1   Hepatology & Gastroenterology Section, Imperial College, London, United Kingdom
› Author Affiliations
Further Information

Publication History

Publication Date:
29 April 2014 (online)

   Permissions and Reprints

Abstract

With the advent of all oral direct-acting antiviral drugs with a broad range of genotypic activity and a low incidence of side effects, we are entering an exciting new era in the therapeutics of hepatitis C virus (HCV). However, it is not yet clear who will benefit from these innovations: Will the advantages be limited to HCV patients in industrialized nations or could the whole community of HCV-infected individuals be given access to treatment? As the majority of people infected with HCV live in resource-limited settings it is important to overcome the barriers that restrict access to treatment in these areas. Drug costs, public and professional education, simplified diagnostics, and political imperative all need to be addressed before the majority of HCV-infected individuals can benefit from the new generation of HCV antivirals.

Keywords

hepatitis C virus - chronic hepatitis C - prevalence - access to treatment - resource-limited countries - direct-acting antivirals