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Semin intervent Radiol 2014; 31(02): 180-186
DOI: 10.1055/s-0034-1373792
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Image-Guided Percutaneous Ablation of Hepatic Malignancies

Gretchen Foltz
1   Division of Interventional Radiology, Mallinckrodt Institute of Radiology, St. Louis, Missouri
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Publikationsdatum:
21. Mai 2014 (online)

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Abstract

The liver is a common site of primary and secondary malignancies, often resulting in significant morbidity and mortality. Evaluating these patients in a multidisciplinary setting allows for optimal utilization of all oncologic therapies including surgery, radiation, systemic chemotherapy, transarterial therapies, and ablation. While surgical intervention often provides the best outcomes when treating most hepatic tumors, many patients are not surgical candidates due to extensive tumor burden, underlying liver disease, or other comorbid conditions. The evolution of imaging and ablation devices has allowed for the increased utilization of percutaneous ablation as definitive and palliative treatment of primary and metastatic hepatic malignancies. Ablation induces tumor necrosis by injection of chemicals (chemical ablation) or temperature modification (thermal ablation). The goal of this review is to provide an overview of different ablation techniques commonly used for hepatic malignancies, discuss the oncologic outcomes of these interventions, and outline the current indications, contraindications, and reported complications of these therapies.

Keywords

percutaneous ablation - hepatocellular carcinoma - hepatic metastases - interventional radiology