Gastrointestinal bleeding

A number of interesting abstracts on gastrointestinal bleeding and endoscopy were presented at Digestive Disease Week (DDW) this year (3 – 6 May 2014, Chicago, Illinois). The following abstracts are those that have particular high clinical importance and the potential for direct impact on the endoscopic care of patients with gastrointestinal bleeding.

• References

• 1 American College of Gastroenterology. Management of patients with ulcer bleeding. Available from: http://gi.org/guideline/management-of-patients-with-ulcer-bleeding/ (Accessed June 2014)
• 2 Gralnek IM, Barkun AN, Bardou M. Management of acute bleeding from a peptic ulcer. N Engl J Med 2008; 359: 928-937
• 3 Barkun AN, Bardou M, Kuipers EJ et al. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med 2010; 152: 101-113
• 4 Sachar H, Vaidya K, Laine L. Intermittant PPI therapy is non-inferior to guideline recommended bolus-continuous infusion PPI therapy after endoscopic hemostasis in patients with ulcer bleeding: a systematic review and meta-analysis. Gastroenterology 2014; 146: 75
• 5 Lau JY, Wong K, Chiu PW et al. Early angiographic embolization after endoscopic hemostasis to high risk bleeding peptic ulcers improves outcomes. Gastrointest Endosc 2014; 79: AB113
• 6 Lau JY, Wong K, Chiu PW et al. Transarterial angiographic embolization vs. surgery in patients with bleeding peptic ulcers uncontrolled at endoscopy: a multicenter randomized trial. Gastrointest Endosc 2014; 79: AB113
• 7 Wu P, Szczesniak MM, Craig PI et al. A novel predictor of rebleeding in high risk peptic ulcer disease selects patients who would benefit most from prophylactic arterial embolisation. Gastroenterology 2014; 146: 183
• 8 Chan FKL, Cheong PK, Ching J et al. Proton-pump inhibitor (PPI) versus histamine-2 receptor antagonist (H2RA) for the prevention of recurrent upper gastrointestinal (UGI) bleeding in high-risk users of low dose aspirin (ASA): an interim analysis. Gastroenterology 2014; 146: 208
• 9 Rockey DC, Melo SW, Ahn C. A randomized controlled trial of nasogastric tube placement in patients with upper gastrointestinal bleeding. Gastroenterology 2014; 146: 184
• 10 Skinner MJ, Gutierrez JP, Neumann H et al. Over-the-scope-clip is an effective rescue therapy for severe acute upper gastrointestinal bleeding. Gastrointest Endosc 2014; 79: AB143
• 11 Sulz MC, Frei R, Gubler C et al. Hemospray for GI bleeding: prospective two-center experience in Switzerland. Gastrointest Endosc 2014; 79: AB226
• 12 Haddara S, Branche J, Lecleire S et al. A novel hemostatic powder for the endoscopic treatment of gastrointestinal bleeding: results from a multicenter prospective study performed in routine practice (the ‘graphic’ registry). Gastroenterology 2014; 146: 771
• 13 Koyama S, Kato T. Absolute ethanol is a highly effective agent in injection therapy of bleeding tract gastric ulcer: ulcer enlargement is not a complication but could be proof of hemostasis. Gastrointest Endosc 2014; 79: AB227-AB228
• 14 Chan FKL, Ki ELL, Tse YK et al. Resumption of low-dose aspirin and the risk of recurrent lower GI bleeding and CV outcomes: a long term cohort study. Gastroenterology 2014; 146: 27
• 15 Oh SK, Kim DJ, Kang DH et al. Endoscopic yield and outcomes of performing urgent versus early endoscopy in acute non-variceal upper gastrointestinal bleeding. Gastrointest Endosc 2014; 79: AB296
• 16 Matsuda T, Okuzono T. Efficacy and safety of emergency balloon-assisted endoscopy in patients with overt ongoing obscure gastrointestinal bleeding. Gastrointest Endosc 2014; 79: AB150
• 17 Marmo R, Bianco MA, Bucci C et al. Liberal transfusion strategy as a potential risk factor for mortality in acute non-variceal upper gastrointestinal bleeding (NVUGIB). Gastrointest Endosc 2014; 79: AB141
• 18 Jensen DM, Ohning GV. Doppler endoscopic probe as a guide to risk stratification and prophylaxis to prevent delayed post-polypectomy induced ulcer hemorrhage after polypectomy. Gastrointest Endosc 2014; 79: AB567
• 19 Siddhi SS, Dalziel H, Henry EB. Initial experience with radiofrequency ablation in gastric antral vascular ectasia and radiation proctitis. Gastrointest Endosc 2014; 79: AB334
• 20 Tang YM, Wang Y, Wang WW. Elective endotracheal intubation prior to emergent EGD in patients with suspected variceal hemorrhage: an evaluation of outcome and complications. Gastrointest Endosc 2014; 79: AB515-AB516
• 21 Kochhar G, Navaneethan U, Parungao JM et al. Short term mortality in patients with acute gastric variceal bleeding: endoscopic glue injections are as effective as TIPS – a comparative study. Gastrointest Endosc 2014; 79: AB227