Kardiologie up2date, Inhaltsverzeichnis Kardiologie up2date 2014; 10(03): 179-194DOI: 10.1055/s-0034-1378067 Thrombozyten und Gerinnungssystem bei kardiovaskulären Erkrankungen © Georg Thieme Verlag KG Stuttgart · New York Interventioneller Vorhofohrverschluss bei Vorhofflimmer-Patienten mit hohem Blutungsrisiko Christoph Mues , Karim Ibrahim , Ruth Strasser Artikel empfehlen Abstract Artikel einzeln kaufen Alle Artikel dieser Rubrik Abstract Atrial fibrillation is the most common sustained cardiac arrhythmia worldwide. The left atrial appendage (LAA) is the main source of thrombi caused by atrial fibrillation because of decreased blood velocity. These thrombi can cause thrombembolic events in leaving the LAA into the systemic circulation. For preventing thromboembolic events a long-term oral anticoagulation therapy is recommended. 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