Palladium-Catalyzed Asymmetric Allylic Alkylation Reaction of 2-Mono­substituted Indolin-3-ones

Abstract

An efficient and practical method was developed for the synthesis of 2,2-disubstituted indolin-3-ones by palladium-catalyzed asymmetric allylic alkylation. Enantioselective construction of quaternary carbon centers was also realized in this way.

Key words

palladium - allylic substitution - asymmetric catalysis - indolines - quaternary carbon

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