Synthesis of Ketenaminals via Catalyst-Free Hydroamination of Ynamides and Diphenylsulfonimide

Abstract

A novel regio- and stereoselective synthesis of ketenaminals by catalyst-free hydroamination of ynamides with diphenylsulfonimide under mild conditions is reported. In addition, N-sulfonylamidines are prepared via subsequent desulfonylation reaction.

Key words

amides - amination - imides - alkynes - sulfonamides - desulfonylation

• References


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