Synthesis 2015; 47(12): 1775-1779
DOI: 10.1055/s-0034-1380147
paper
© Georg Thieme Verlag Stuttgart · New York

An Unsymmetrical Iron Catalyst for the Asymmetric Transfer Hydrogenation­ of Ketones

Samantha A. M. Smith
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada   Email: robert.morris@utoronto.ca
,
Robert H. Morris*
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada   Email: robert.morris@utoronto.ca
› Author Affiliations
Further Information

Publication History

Received: 12 December 2014

Accepted: 14 January 2015

Publication Date:
20 February 2015 (online)


Abstract

A new iron(II)(Ph2P–NH–N–PCy2) complex with a dicyclohexylphosphino group trans to the NH group was found to catalyze the asymmetric transfer hydrogenation of a variety of ketones with high enantioselectivity.

Supporting Information