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Synthesis 2015; 47(18): 2731-2737
DOI: 10.1055/s-0034-1380419
DOI: 10.1055/s-0034-1380419
special topic
Metal-Free [3+2] Oxidative Coupling of Phenols with Alkenes: Synthesis of Dihydrobenzofurans
Weitere Informationen
Publikationsverlauf
Received: 11. März 2015
Accepted after revision: 14. April 2015
Publikationsdatum:
27. Mai 2015 (online)
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Abstract
Herein, we demonstrated a benign and metal-free [3+2]-cycloaddition reaction using simple and readily available phenols and styrenes as substrates and sodium persulfate as an inexpensive and environmentally friendly oxidant for the direct synthesis of dihydrobenzofurans. This methodology was applied to the synthesis of corsifuran A in a single step.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0034-1380419.
- Supporting Information
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